Results 31 to 40 of about 16,373 (288)

Primary postpartum haemorrhage

Journal of Obstetrics and Gynaecology, 2002
Postpartum haemorrhage (PPH) is the leading cause of maternal death worldwide. In the developing countries, it is responsible for the death of about 125 000 women each year. Death from postpartum haemorrhage is eminently preventable. It is essential that first-line staff are able to prevent, make early diagnosis and provide prompt management of primary
openaire   +2 more sources

Women who experience obstetric haemorrhage are at higher risk of anaemia, in both rich and poor countries.

, 2011
OBJECTIVES: Anaemia is a potential long-term sequel of obstetric blood loss, but the increased risk of anaemia in women who experience a haemorrhage compared to those who do not has not been quantified.
Ganaba, R, V. Filippi, Wagner, KS, Calvert, C, A. Adler, R. Ganaba, Ronsmans, C, Thomas, SL, S. L. Thomas, Goufodji, S, C. Calvert, Filippi, V, S. Goufodji, K. S. Wagner, C. Ronsmans, Adler, A   +15 more
core   +1 more source

Haemostasis during pregnancy, labour and postpartum haemorrhage

, 2012
Background: Haemostatic disorders are common in obstetric complications and may result in more severe complications if not detected. There is limited knowledge about viscoelastic methods, fibrinogen and Factor XIII and how they are related to each other ...
Karlsson, Ove,, Karlsson, Ove, Hillarp, Andreas, Hellgren, Margareta,, Hellgren, Margareta, Sporrong, Tommy, Jeppsson, Anders,, Jeppsson, Anders   +7 more
core   +1 more source

Postpartum Haemorrhage Risk Prediction Model Developed by Machine Learning Algorithms: A Single-Centre Retrospective Analysis of Clinical Data

Clinical and Experimental Obstetrics & Gynecology
Background: Postpartum haemorrhage (PPH) is a serious complication and a cause of maternal mortality after delivery. This study used machine learning algorithms and new feature selection methods to build an efficient PPH risk prediction model and ...
Wenhuan Wang, Chanchan Liao, Hongping Zhang, Yanjun Hu   +3 more
doaj   +1 more source

Lilrb4a Suppression Reprograms Microglia to Mitigate APOE4‐Associated Amyloid Plaques and Cerebral Amyloid Angiopathy in Association With a PPAR‐Linked Pro‐Clearance State

Advanced Science, EarlyView.
Targeting Lilrb4a in Apolipoprotein E4 (APOE4)‐associated Alzheimer's disease (AD) reprograms microglia toward a beneficial, phagocytic state. Genetic deletion or antisense inhibition of Lilrb4a suppresses p‐SHP2/NF‐κB/STAT1 signaling, restores PPAR‐linked lipid and energy metabolism, and reduces amyloid plaque burden and cerebral amyloid angiopathy ...
Changxu Nie, Ruixi Yang, Xiaotong Wang, Ping Jia, Xueqi Zhang, Yaqi Dai, Xue Bai, Sijia Duan, Yufeng Li, Peng Zheng, Xin Tian, Li Jiang, Chao Wang   +12 more
wiley   +1 more source

CIRSE standards of practice on gynaecological and obstetric haemorrhage

CVIR Endovascular, 2020
This CIRSE Standards of Practice document provides best practices for obstetric haemorrhage embolisation (OHE) in the management of postpartum haemorrhage (PPH).
Thomas Rand, Rafiuddin Patel, Wolfgang Magerle, Raman Uberoi   +3 more
doaj   +1 more source

Prmt6 Deficiency or Inhibition Restores Microglial Homeostasis and Promotes Scar‐Limited Repair in Adult Spinal Cord Injury

Advanced Science, EarlyView.
After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng, Zhengqiang Wu, Yu Xiong, Zhongya Gao, Yishan Liu, Ziyi Wang, Haibin Wang, Chaofeng Han, Wenxiang Chu, Xuhua Lu   +9 more
wiley   +1 more source

A Skull Bone Marrow‐to‐Brain Axis Links Osteoblastic Activity to Myeloid Cell Trafficking, Cerebral Blood Flow, and Cognition in Alzheimer's Progression

Advanced Science, EarlyView.
This study reveals that Alzheimer's disease–linked APP expression in bone‐forming cells drives skull bone marrow remodeling and alters its vascular connections to the brain. These changes disrupt immune cell trafficking, cerebral blood flow, and cognition. Targeting bone marrow macrophages restores brain function, highlighting a previously unrecognized
Lei Xiong, Dong Sun, Hao‐Han Guo, Daehoon Lee, Zhipeng Liu, Lin Mei, Wen‐Cheng Xiong   +6 more
wiley   +1 more source

Xenogeneic Mitochondrial Transplantation Improves Selected Age‐Associated Phenotypes in Mice

Advanced Science, EarlyView.
Yak‐derived xenogeneic mitochondrial transplantation improves selected age‐associated phenotypes in mice, enhances mitochondrial functional readouts, and engages host mitochondrial quality‐control pathways. Broad tissue biodistribution, increased ATP production and mtDNA copy number, reduced ROS levels and dysfunctional mitochondria, improved motility ...
Wenpeng Li, Xijia Wang, Yaning Hu, Zhen Yang, Tian Niu, Xingbo Zhao   +5 more
wiley   +1 more source

Clinical and Laboratory Characterization of Acquired Von Willebrand Syndrome

American Journal of Hematology, EarlyView.
ABSTRACT Acquired von Willebrand Syndrome (AVWS) is a rare bleeding disorder characterized by quantitative or qualitative defects of von Willebrand factor (VWF) in patients without a personal or family history of bleeding. It is frequently associated with systemic diseases, particularly lymphoproliferative disorders (LPDs) and myeloproliferative ...
Alessandro Ciavarella, Luciano Baronciani, Omid Seidizadeh, Paola Colpani, Elio Ingenito, Daniele Cattaneo, Maria Teresa Pagliari, Addolorata Truma, Alessandra Iurlo, Simona Maria Siboni, Flora Peyvandi   +10 more
wiley   +1 more source