This study reveals that the glycolytic enzyme HK2 mediates hypoxia‐induced astrocytic exosome biogenesis by directly phosphorylating nSMase1. These astrocytic exosomes impair brain endothelial tight junctions. Astrocyte‐specific knockdown of HK2 reduces exosome release and alleviates brain injury after MCAO.
Chen Chen+12 more
wiley +1 more source
Level of mother-baby bonding and influencing factors during pregnancy and postpartum period.
BACKGROUND Bonding is the process of an emotional relationship between mothers and babies. Pregnancy and postpartum periods are most important of developing a mother-child bonding.
G. Daglar, Naim Nur
semanticscholar +1 more source
Breastfeeding as a Mechanism to Reduce Postpartum Depression with Weight as a Major Contributing Factor in Hispanic Women [PDF]
Postpartum Depression (PPD) is the most common childbearing-related illness around the globe affecting both mothers and their children; yet minimal longitudinal research has been done to study the effect of depressive symptomatology on breastfeeding ...
Wilson, Celia
core +1 more source
Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu+17 more
wiley +1 more source
Sleep Quality and Quality of Life in Postpartum Woman
Objective:This aim of study was to investigate the quality of sleep and life in postpartum period women.Materials and Methods:This cross-sectional study was carried out on 632 women (n=316 postpartum period, n=316 healthy control) who applied to ...
Özge Erçel, Hatice Kahyaoğlu Süt
doaj +1 more source
Maternal brain resting‐state connectivity in the postpartum period
In the postpartum period, the maternal brain experiences both structural and functional plasticity. Although we have a growing understanding of the responses of the human maternal brain to infant stimuli, little is known about the intrinsic connectivity ...
A. Dufford, Andrew Erhart, P. Kim
semanticscholar +1 more source
Beberapa Faktor yang Mempengaruhi Kepatuhan Bidan Desa dalam Pemberian Konseling KB Postpartum pada Ibu Pasca Persalinan di Kabupaten Semarang Tahun 2014 [PDF]
Universitas Diponegoro Fakultas Kesehatan Masyarakat Program Magister Ilmu Kesehatan Masyarakat Konsentrasi Kesehatan Ibu dan Anak 2014 ABSTRAK Nugraheni Kusumawati Beberapa Faktor yang Mempengaruhi Kepatuhan Bidan Desa dalam Pemberian ...
Istiarti, Tinuk+2 more
core
A Close and Supportive Interparental Bond During Pregnancy Predicts Greater Decline in Sexual Activity From Pregnancy to Postpartum: Applying an Evolutionary Perspective [PDF]
A common topic for advice given to parents after childbirth – both from relationship experts and popular media – is how to “bounce back” to one’s pre-pregnancy sexuality, with warnings that postpartum declines in sexual frequency will take a serious toll
Brock, Rebecca L+2 more
core +2 more sources
HOP, an innovative ICT‐based fluorescent probe, visualizes H2O2 in stressed neurons while locally releasing serotonin (5‐HT) for real‐time protein interaction mapping. Its unique tandem sensing and labeling strategy reveals 5‐HT's role under oxidative stress, offering a powerful tool for neurophysiological research and therapeutic discovery.
Yani Liu+9 more
wiley +1 more source
Background The postpartum period is a critical period for addressing widespread unmet needs in family planning and for reducing the risks of closely spaced pregnancies.
Marta Berta+4 more
semanticscholar +1 more source