Results 41 to 50 of about 2,162 (176)

Novel Variants in KMT2C Further Support a Neurodevelopmental Disorder Distinct From Kleefstra and Kabuki Syndromes

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 4, April 2026.
Sedlackova et al. describe detailed phenotypes of three patients with novel variants in the KMT2C gene. After detailed phenotypic analysis, we found that our patients have phenotypes very similar to those previously described as KMT2C‐related Kleefstra syndrome 2, and thus further extend the list of KMT2C causal variants.
Lucie Sedláčková   +3 more
wiley   +1 more source

Effects of Thyroid Peroxidase Antibody on Maternal and Neonatal Outcomes in Pregnant Women in an Iodine-Sufficient Area in China

open access: yesInternational Journal of Endocrinology, 2016
Purposes. To evaluate the effects of thyroid peroxidase antibodies (TPOAb) on maternal and neonatal adverse outcomes in pregnant women. Methods. 208 pregnant women at 24–28 weeks were divided into two groups, TPOAb-positive and TPOAb-negative groups ...
Xi Chen   +6 more
doaj   +1 more source

Evaluation of the Efficacy and Safety of Satralizumab in a Pregnant NMOSD Patient With AQP4/MOG‐IgG Dual Seropositive: A Case Report

open access: yesAnnals of Clinical and Translational Neurology, Volume 13, Issue 3, Page 633-638, March 2026.
ABSTRACT Neuromyelitis Optica Spectrum Disorder (NMOSD) is a chronic autoimmune neuroinflammatory disease, typically characterized by antibodies against aquaporin 4 (AQP4‐IgG) or myelin oligodendrocyte glycoprotein (MOG‐IgG). Simultaneous seropositivity for both antibodies in a single patient is exceedingly rare.
Yeting Luo, Shuhua Xie, Xianghong Liu
wiley   +1 more source

Association Between Autoimmune Thyroiditis and Cervical Artery Dissection: A Retrospective Cohort Study

open access: yesHealth Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Limited evidence suggests autoimmune thyroiditis (AT) could represent a risk factor for cervical artery dissection (CeAD). We tested the hypothesis of a positive association between AT and CeAD within 3 years following diagnosis compared to matched euthyroid controls.
Robert J. Trager   +2 more
wiley   +1 more source

Atrophic hypothyroidism associated with thyrotropin receptor antibodies [PDF]

open access: yesEinstein (São Paulo)
Hypothyroidism is most frequently caused by Hashimoto's thyroiditis. While thyrotropin receptor antibodies are well-known in Graves’ disease-induced hyperthyroidism, their role in hypothyroidism is emerging. We report the case of a 37-year-old woman with
Marcos Tadashi Kakitani Toyoshima   +5 more
doaj   +1 more source

Sex Matters: Hormonal and Chromosomal Determinants of Autoimmunity and Anti‐Cancer Immunity Across the Lifespan

open access: yesImmunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Sex plays a key role in shaping both anti‐cancer immunity and autoimmunity. Biological factors underlying sexual dimorphism have now been identified in multiple aspects of anti‐cancer immunity and autoimmunity. These factors include sex differences in hormone levels, chromosome complement, and expression of the long non‐coding RNA XIST.
Christian G. Bustillos   +4 more
wiley   +1 more source

Personalized Models of Biological Barriers and Their Diseases: Recent Progress with Organs‐On‐Chips

open access: yesAdvanced Biology, Volume 10, Issue 2, February 2026.
Buck and Bugter et al. explore the architectural diversity and physiological functions of human barrier systems and reveal how organ‐on‐chip platforms, particularly those integrating patient‐derived cells, are advancing barrier disease modeling. They highlight how emerging biological and technological advances can be used to bridge the gap between ...
Franziska Buck   +4 more
wiley   +1 more source

Alteração tireoidiana: um fator de risco associado à depressão pós-parto? Thyroid dysfunction: a risk factor associated with post-partum depression?

open access: yesRevista Brasileira de Saúde Materno Infantil, 2009
OBJETIVOS: estudar prevalência de depressão pósparto e sua correlação com alterações tireoidianas maternas. MÉTODOS: estudo observacional descritivo transversal realizado com 292 mulheres entre 31 e 180 dias após o parto, atendidas em unidades de saúde ...
Gustavo Enrico Cabral Ruschi   +5 more
doaj   +1 more source

Targeted Antenatal Screening for Predicting Postpartum Thyroiditis and Its Evolution Into Permanent Hypothyroidism

open access: yesFrontiers in Endocrinology, 2020
Postpartum thyroiditis (PPT) has a prevalence of 1–22%, with an ~50% rate of evolution into permanent hypothyroidism (PH). PPT risk is assessed by measuring serum thyroid antibodies during gestation, as 1/3–1/2 of Ab+ve pregnant women will develop PPT ...
Salvatore Benvenga   +2 more
doaj   +1 more source

Study for Optimal Dose Determination of Levothyroxine in Subclinical Hypothyroid Pregnant Patients: A Prospective Observational Study

open access: yesRUHS Journal of Health Sciences, 2023
Introduction: Subclinical hypothyroidism in pregnancy is associated with early pregnancy loss, preterm birth, abruptio placentae, and postpartum thyroiditis. The aim of this study was to analyze the optimal dose of st nd rd Levothyroxine given during 1 ,
Yogita Gupta, Usha Agarwal
doaj   +1 more source

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