Results 61 to 70 of about 182,863 (189)

Targeting Senescence with Apigenin Improves Chemotherapeutic Efficacy and Ameliorates Age‐Related Conditions in Mice

open access: yesAdvanced Science, EarlyView.
As a plant‐derived flavonoid, apigenin directly targets PRDX6 to inhibit its PLA2 activity, blocking HSPA8 activation and disturbing its interactions with ATM and p38MAPK in senescent cells. By dampening wide spectrum expression of the SASP, apigenin prevents loss of tissue homeostasis, improves organ function, and alleviates multiple age‐related ...
Hongwei Zhang   +10 more
wiley   +1 more source

A Local Inverse Formula and a Factorization [PDF]

open access: yesarXiv, 2016
When a matrix has a banded inverse there is a remarkable formula that quickly computes that inverse, using only local information in the original matrix. This local inverse formula holds more generally, for matrices with sparsity patterns that are examples of chordal graphs or perfect eliminators.
arxiv  

The Rise of Chalcohalide Solar Cells: Comprehensive Insights From Materials to Devices

open access: yesAdvanced Science, EarlyView.
This review provides a detailed overview of recent advancements in chalcohalide solar cells, focusing on structure design, material chemistry, synthesis methods, and device optimization. It also highlights future directions for improving device efficiency through innovative device architectures and synthesis techniques, addressing key challenges in ...
Hongrui Zhang   +7 more
wiley   +1 more source

Bivalent Gadolinium Ions Forming Injectable Hydrogels for Simultaneous In Situ Vaccination Therapy and Imaging of Soft Tissue Sarcoma. [PDF]

open access: yesAdv Healthc Mater, 2023
Wang C   +17 more
europepmc   +1 more source

Targeting Splenic Myeloid Cells with Nanobiologics to Prevent Postablative Pancreatic Cancer Recurrence via Inducing Antitumor Peripheral Trained Immunity

open access: yesAdvanced Science, EarlyView.
Using a preclinical pancreatic cancer model, we identified that tumor progression restructures splenic immunity via myeloid cell expansion. MDCa@RBC‐Alipo nanobiologics were engineered to epigenetically and metabolically reprogram splenic myeloid cells, alleviating post‐ablation immunosuppression.
Shengbo Wu   +12 more
wiley   +1 more source

High‐Fidelity Computational Microscopy via Feature‐Domain Phase Retrieval

open access: yesAdvanced Science, EarlyView.
An innovative phase retrieval framework, termed FD‐PR, is uniquely established in the image's feature domain through the feature‐extracted, physical‐driven regression with interfaces for combining physics and image processing constraints. FD‐PR takes advantage of invariance components of an image against presences of model mismatch and uncertainty ...
Shuhe Zhang   +4 more
wiley   +1 more source

Functional normalizing flow for statistical inverse problems of partial differential equations [PDF]

open access: yesarXiv
Inverse problems of partial differential equations are ubiquitous across various scientific disciplines and can be formulated as statistical inference problems using Bayes' theorem. To address large-scale problems, it is crucial to develop discretization-invariant algorithms, which can be achieved by formulating methods directly in infinite-dimensional
arxiv  

High‐Speed 3D Printing Coupled with Machine Learning to Accelerate Alloy Development for Additive Manufacturing

open access: yesAdvanced Science, EarlyView.
This work shows combining high‐throughput experiments of metal 3D printing with data science‐driven prediction leads to faster alloy development. Researchers develop steel alloy specimens specifically for 3D printing by adjusting aluminum content (0–10 wt.%) and energy input during printing.
Avinash Hariharan   +7 more
wiley   +1 more source

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