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Postsynaptic potential summation and action potential initiation: function following form.
The mechanisms and physiological significance of postsynaptic potential summation and action potential initiation are among the most difficult concepts for students to grasp. To help students understand these concepts, we emphasize that neurons have three distinct functional zones: 1 ) the ...
M. Giuliodori, G. Zuccolilli
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Origin of ganglionic inhibitory postsynaptic potential.
Life Sciences, 1967S. Nishi, K. Koketsu
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Detection of Spontaneous Postsynaptic Potentials
Computers and Biomedical Research, 1995The amplitude and time course of postsynaptic potentials (PSPs) recorded by intracellular techniques contain information that allow different synaptic events to be detected. In the present paper an algorithm to detect spontaneous PSPs is described. The algorithm is based on computation of approximations of first and second derivatives of the signals ...
P J, Franaszczuk, G K, Bergey, P, Kudela
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Mechanisms of slow postsynaptic potentials
Nature, 1981Classical views of synaptic transmission have to be modified to take account of slow postsynaptic potentials (p.s.ps), which are often mediated by novel ionic and molecular mechanisms and which are sometimes evoked by neuropeptides. Understanding slow p.s.ps will provide insights into the mechanisms of biological signal transduction and long-term ...
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Primary afferent hyperpolarization without postsynaptic potentiation
Experimental Neurology, 1973Abstract Tetanization of a cutaneous afferent pathway does not lead to potentiation of postsynaptic activity but it produces a decrease in excitability of the pathway's central terminals and an increase in the threshold of the dorsal root reflexes evoked in the same fibers by stimulation of adjacent pathways.
E J, Carregal, B L, Crue
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Psychopharmacology bulletin
The postsynaptic density (PSD) is an ultrastructural specialization of the glutamatergic excitatory synapses, at the cytosolic surface of the postsynaptic membrane of dendritic spines. The PSD is a highly organized transductional machinery that tunes the
A. de Bartolomeis, F. Iasevoli
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The postsynaptic density (PSD) is an ultrastructural specialization of the glutamatergic excitatory synapses, at the cytosolic surface of the postsynaptic membrane of dendritic spines. The PSD is a highly organized transductional machinery that tunes the
A. de Bartolomeis, F. Iasevoli
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Inhibitory Postsynaptic Potentials in Grasshopper Muscle
Science, 1964Hyperpolarizing inhibitory postsynaptic potentials have been discovered in fibers of the "jumping" muscle of the grasshopper. These potentials attenuate the depolarizing excitatory postsynaptic responses. They are enhanced during depolarization of the muscle fiber with applied current and are diminished and then reversed during hyperpolarization.
P N, USHERWOOD, H, GRUNDFEST
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Neuroscience, 1995
Tetanic stimulation of afferents in the stratum radiatum of the CA1 area of the rat hippocampus results in long-term potentiation of excitatory synaptic responses in pyramidal cells. Previous studies have reported a greater increase in the population spike amplitude following the induction of long-term potentiation than could be accounted for by the ...
C, Bernard, H V, Wheal
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Tetanic stimulation of afferents in the stratum radiatum of the CA1 area of the rat hippocampus results in long-term potentiation of excitatory synaptic responses in pyramidal cells. Previous studies have reported a greater increase in the population spike amplitude following the induction of long-term potentiation than could be accounted for by the ...
C, Bernard, H V, Wheal
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Quantum analysis of postsynaptic potentials
Neurophysiology, 1979Basic formulations of the quantum theory for synaptic transmission are listed. Methods for determining the mean quantum content, quantum value and binomial parameters describing the amplitude distributions of the unitary and "minimal" postsynaptic potentials are discussed.
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Ion channels and postsynaptic potentials
Biophysical Chemistry, 1988Neurotransmitters open transmembrane ion channels in target membranes. At the motor endplate, the open time of channels activated by acetylcholine determines the time course of the endplate current. Endplate channels are selective for cations and their conductance and open times are influenced by the nature of the permeating cation.
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