Results 161 to 170 of about 71,707 (290)

Multiomics analyses reveal that PRMT5 regulates membrane transport and cholesterol synthesis in white adipocytes

open access: yesiMetaOmics, EarlyView.
Prmt5AKO downregulates genes related to fatty acid transport and triacylglycerol synthesis, while upregulating genes involved in glucose transport and cholesterol biogenesis. These changes cause alternation in lipid composition and metabolic phenotypes of Prmt5AKO mice. Abstract The adipose tissue (AT) is a main regulator of systemic energy homeostasis,
Xiyue Chen   +7 more
wiley   +1 more source

Posttranslational modification of Aurora A-NSD2 loop contributes to drug resistance in t(4;14) multiple myeloma. [PDF]

open access: yesClin Transl Med, 2022
Jiang H   +13 more
europepmc   +1 more source

Mid‐Regional Proadrenomedullin in Cerebrospinal Fluid Is a Reliable Diagnostic and Prognostic Marker for Acute Meningoencephalitis and Neurological Disorders

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
MR‐ProADM levels reflect Adrenomedullin response to BBB damage. CSF levels are quite variable across different neurological syndromes, but they are particularly high in acute CNS infections, which makes MR‐ProADM a promising additional diagnostic and prognostic biomarker in this setting.
Francesco Janes   +13 more
wiley   +1 more source

Posttranslational modification of the RHO of plants protein RACB by phosphorylation and cross-kingdom conserved ubiquitination. [PDF]

open access: yesPLoS One, 2022
Weiß L   +11 more
europepmc   +1 more source

UBE3A Inhibits Trophoblast Cell Migration and Invasion by Promoting ITGB1 Degradation and Affecting PI3K/AKT Signaling

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Preeclampsia (PE) is an obstetric disease that is characterized by reduced migration and invasion of placental trophoblast cells. Here, the effects of the E3 ubiquitin ligase UBE3A on the migration and invasion of trophoblast cells were evaluated.
Xiu‐Jun Li   +5 more
wiley   +1 more source

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