UFL1‐Mediated UFMylation of ENO1 Restrains Aerobic Glycolysis and Colorectal Cancer Progression
UFMylation restrains aerobic glycolysis and colorectal cancer progression by modifying the glycolytic enzyme ENO1. Pharmacological enhancement of the UFL1–ENO1 interaction by the FDA‐approved antibiotic torezolid promotes ENO1 UFMylation, suppresses tumor metabolism, and sensitizes colorectal cancer to chemotherapy, revealing an actionable metabolic ...
Xiuqing Ma +14 more
wiley +1 more source
Sex-Specific Differences in Neuromuscular Performance, Joint Mobility, and Postural Control in Elite Karate Athletes. [PDF]
Molinaro L +3 more
europepmc +1 more source
Endothelial YAP Signaling Promotes Blood‐Spinal Cord Barrier Repair in Mice After Spinal Cord Injury
Endothelial YAP is required for blood‐spinal cord barrier repair after spinal cord injury. YAP‐dependent vascular repair is associated with ANGPT1/PI3K/AKT signaling in vivo and may involve endothelial‐pericyte paracrine interactions. By supporting vascular remodeling, tight junction restoration, restored pericyte coverage, and astrocyte‐vascular ...
Jiawei Wang +14 more
wiley +1 more source
Tri‐WOB: A Bistability‐Driven Variable Stiffness Origami Structure for Soft Robotic Arms
Inherent bistability in Waterbomb origami enables the Tri‐WOB to switch between compliant and stiff states. By stacking multiple modules, the robotic arm maintains stiffness without continuous energy input while achieving large contraction, free morphing, and load‐bearing/transportation capability.
Lingchen Kong, Yaoyao Fiona Zhao
wiley +1 more source
Changes in postural control in older adults: a five-year longitudinal study. [PDF]
Nohelova D +4 more
europepmc +1 more source
Paraborg: Paramedic Cyborg Insects for In Situ Emergency Drug‐Delivery
This work introduces Paraborg, a human‐supervised paramedic cyborg‐insect platform that combines controllable locomotion, onboard imaging, and an auto‐injection mechanism for in situ drug‐delivery. By demonstrating reliable navigation, target stabilization, injector launch, and multi‐insect teamwork, the study extends cyborg insects from survivor ...
H. Nhan Le +5 more
wiley +1 more source
An Exploratory Analysis of Postural Control in People with Type 2 Diabetes Mellitus Using a Smartphone IMU Sensor. [PDF]
Thomsen TR +5 more
europepmc +1 more source
Leveraging the chemical similarity between Ga3+ and Fe3+ as well as the antioxidant properties of quercetin, gallium–quercetin nanoparticles (GQNPs) were prepared to integrate iron homeostasis regulation, oxidative stress suppression, and mitochondrial protection for multi‐target ferroptosis inhibition in Parkinson's Disease.
Keyang Xu +12 more
wiley +1 more source
Postural Control During Single-Leg Stance Under Degraded and Occluded Visual Conditions in Healthy Young Adults. [PDF]
Chalkia A +6 more
europepmc +1 more source
Ion‐Gating Reservoir Computing for Preprocessing‐Free Speech Recognition from Throat Vibrations
This work presents a throat‐mounted mechanoelectric sensor integrated with an ion‐gel/graphene reservoir device for on‐device speech recognition. The system converts raw biomechanical vibrations into rich nonlinear current dynamics, enabling efficient classification through a simple linear readout. The approach highlights a compact and tunable physical‐
Daiki Nishioka +5 more
wiley +1 more source

