Results 71 to 80 of about 11,551 (253)

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu, Alex Liang, Benjamin U. Hoffman, Dawn M. Schiehser, Oliver Case, Alan Simmons, Ruth Klaming, Andres Gottfried‐Blackmore, Ravinder K. Mittal, Christopher Puleo, Hubert Lim, Imanuel Lerman   +11 more
wiley   +1 more source

POTS and Antiphospholipid Syndrome: An Unlikely Association

Case Reports in Rheumatology, 2021
Antiphospholipid syndrome is a rare complication of postural orthostatic tachycardia syndrome. Clinically, the presentation has overlapping symptoms of both diseases, with lightheadedness or syncope when moving from a supine to a standing position as ...
Kalvin Zee, Shakaib Qureshi
doaj   +1 more source

Exploring heart rate variability as a biomarker for frailty: A narrative review

European Journal of Clinical Investigation, Volume 56, Issue 4, April 2026.
Frailty arises from progressive multisystem dysregulation, prompting interest in biomarkers that capture declining physiological reserve. This review positions heart rate variability (HRV) within this evolving biomarker landscape, outlining its physiological basis, analytical domains and relevance to clinical research.
Luca Tagliafico, Silvia Ottaviani, Riccardo Balzano, Stefania Peruzzo, Alessio Nencioni, Fiammetta Monacelli   +5 more
wiley   +1 more source

Reliability of orthostatic beat-to-beat blood pressure tests: implications for population and clinical studies [PDF]

, 2017
Objective: To assess the test–retest reliability of orthostatic beat-to-beat blood pressure responses to active standing and related clinical definitions of orthostatic hypotension. Methods: A random sample of community-dwelling older adults from the pan-
A Costa, A Weiss, AAJ Smit, BJ Whelan, C Finucane, C. Finucane, CW Fan, D Ziegler, E O’Brien, G Mancia, G. M. Savva, GL Schwartz, H Cronin, J Belmin, J Conway, J Frewen, J Frith, J Frith, J Lagro, JA Hutcheon, JE Naschitz, JJ Smith, LS Radloff, Moya, MS Hartwig, R Freeman, R Newson, R Romero-Ortuno, R Romero-Ortuno, R. A. Kenny, TJ Gabbett, VK van Wijnen, W Wieling, W Wieling, ZS Nasreddine   +34 more
core   +1 more source

‘What Do People With Long Covid Want From Healthcare Services?’ A Qualitative Exploration From Lived Experience

Health Expectations, Volume 29, Issue 2, April 2026.
ABSTRACT Background Long COVID (LC) is a chronic, multisystem condition affecting millions globally, with significant personal, social and economic consequences. Despite increasing recognition of its impact, healthcare services for LC remain inconsistent with patients frequently encountering fragmented services, scepticism and delays leading to patient‐
Clare Rayner, Nikki Smith, Ruairidh Milne, Ghazala Mir, Johannes de Kock, Nawar Diar Bakerly, The LOCOMOTION Consortium, Nawar Bakerly, Kumaran Balasundaram, Megan Ball, Mauricio Barahona, Alexander Casson, Jonathan Clarke, Karen Cook, Rowena Cooper, Vasa Curcin, Julie Darbyshire, Helen Davies, Helen Dawes, Simon de Lusignan, Brendan Delaney, Carlos Echevarria, Sarah Elkin, Ana Belen Espinosa Gonzalez, Rachael Evans, Sophie Evans, Zacchaeus Falope, Ben Glampson, Madeline Goodwin, Trish Greenhalgh, Darren C. Greenwood, Stephen Halpin, Juliet Harris, Will Hinton, Mike Horton, Samantha Jones, Joseph Kwon, Cassie Lee, Ashliegh Lovett, Mae Mansoubi, Victoria Masey, Harsha Master, Erik Mayer, Bernardo Meza‐Torres, Ruairidh Milne, Ghazala Mir, Jacqui Morris, Adam Mosley, Jordan Mullard, Daryl O'Connor, Rory O'Connor, Thomas Osborne, Amy Parkin, Stavros Petrou, Anton Pick, Denys Prociuk, Clare Rayner, Amy Rebane, Natalie Rogers, Janet Scott, Manoj Sivan, Nikki Smith, Adam Smith, Emma Tucker, Ian Tucker‐Bell, Paul Williams, Darren Winch, Conor Wood   +67 more
wiley   +1 more source

Pyloric Metrics and Distensibility Plateau by Functional Luminal Imaging Probe in Pediatric Patients: A Pilot Study

Neurogastroenterology &Motility, Volume 38, Issue 4, April 2026.
Pediatric patients underwent pyloric functional luminal imaging probe (FLIP) for refractory upper gastrointestinal symptoms. Unlike prior adult studies, pyloric distensibility did not correlate to gastric emptying, and patients with higher distensibility more frequently responded to botulinum toxin. The presence of a distensibility plateau enhanced the
Peter T. Osgood, Natalie V. Hoffmann, Joshua B. Wechsler, Roman Pantazopoulos, John E. Fortunato   +4 more
wiley   +1 more source

Spontaneous intracranial hypotension [PDF]

, 2014
Spontaneous intracranial hypotension (SIH) is uncommon and usually undiagnosed entity which present most commonly with postural headache. The diagnosis is difficult because of the nonspecific symptoms and lack of awareness about the disease .It is ...
Asif, Ahmed, Khan, Amanullah, Reha, Bushra, Sayed, Mehwish   +3 more
core   +2 more sources

A review of postural orthostatic tachycardia syndrome [PDF]

Europace, 2008
A 21-year-old female reports an 18-month history of light-headedness on standing. This is often associated with palpitations and a feeling of intense anxiety. She has had two black-outs in the past 12 months. She is not taking any regular medications. Her supine blood pressure was 126/84 mmHg with a heart rate of 76 bpm, and her upright blood pressure ...
Sheila, Carew, Margaret O, Connor, John, Cooke, Richard, Conway, Christine, Sheehy, Aine, Costelloe, Declan, Lyons   +6 more
openaire   +2 more sources

Gastrointestinal Symptoms and Systemic Comorbidities in Patients With POTS: A Systematic Review and Meta‐Analysis

Neurogastroenterology &Motility, Volume 38, Issue 4, April 2026.
This meta‐analysis reveals that a significant proportion of patients with POTS experience gastrointestinal symptoms. The most prevalent symptoms include nausea, bloating, abdominal pain, and postprandial fullness. There is a notable overlap of POTS with IBS, joint hypermobility, mast cell activation syndrome, and chronic fatigue.
Dmitrii Kulin, Ayesha Shah, Thomas Fairlie, Kyle Staller, Samuel Nurko, Laurie Keefer, Qasim Aziz, Douglas A. Drossman, Michael P. Jones, Gerald Holtmann   +9 more
wiley   +1 more source

Orthostatic symptoms does not always manifest during tilt-table test in pediatric postural orthostatic tachycardia syndrome patients [PDF]

Korean Journal of Pediatrics, 2013
PurposeChronic day-to-day symptoms of orthostatic intolerance are the most notable features of postural orthostatic tachycardia syndrome (POTS). However, we have encountered patients with such symptoms and excessive tachycardia but with no symptoms ...
Tae-Eon Huh, Jung Sook Yeom, Young-Soo Kim, Hyang-Ok Woo, Ji Sook Park, Eun Sil Park, Ji-Hyun Seo, Jae-Young Lim, Chan-Hoo Park, Ki-Jong Park, Hee-Shang Youn   +10 more
doaj   +1 more source