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Adaptive Approaches to Exercise Rehabilitation for Postural Tachycardia Syndrome and Related Autonomic Disorders [PDF]

Archives of Rehabilitation Research and Clinical Translation
Exercise is a well-documented, nonpharmacologic treatment for individuals with autonomic dysfunction and associated orthostatic intolerance, such as postural tachycardia syndrome and related disorders.
Lauren Ziaks, PT, DPT, ATC, Kathryn Johnson, PT, DPT, Kelsi Schiltz, PT, DPT, Ryan Pelo, PT, DPT, PhD, Guillaume Lamotte, MD, MSc, Claudia Dal Molin, DO, RMSK, Tae Chung, MD, Melissa M. Cortez, DO   +7 more
doaj   +3 more sources

Co-creation of a complex, multicomponent rehabilitation intervention and feasibility trial protocol for the PostUraL tachycardia Syndrome Exercise (PULSE) study. [PDF]

Pilot Feasibility Stud, 2023
Background There is a dearth of research to support the treatment of people with postural tachycardia syndrome (PoTS). Despite expert consensus suggesting exercise is recommended for this patient group, there are no randomised control trials examining ...
Pearce G, Holliday N, Sandhu H, Eftekhari H, Bruce J, Timms E, Ablett L, Kavi L, Simmonds J, Evans R, Magee P, Powell R, Keogh S, McGregor G.   +13 more
europepmc   +3 more sources

Noninvasive Vagus Nerve Stimulation in Postural Tachycardia Syndrome: A Randomized Clinical Trial. [PDF]

JACC Clin Electrophysiol, 2023
BACKGROUND Low-level transcutaneous stimulation of the auricular branch of the vagus nerve at the tragus is antiarrhythmic and anti-inflammatory in animals and humans.
Stavrakis S, Chakraborty P, Farhat K, Whyte S, Morris L, Abideen Asad ZU, Karfonta B, Anjum J, Matlock HG, Cai X, Yu X.   +10 more
europepmc   +2 more sources

A predictive model of response to metoprolol in children and adolescents with postural tachycardia syndrome. [PDF]

World J Pediatr, 2023
Background The present work was designed to explore whether electrocardiogram (ECG) index-based models could predict the effectiveness of metoprolol therapy in pediatric patients with postural tachycardia syndrome (POTS).
Xu BW, Zhang QY, Li XY, Tang CS, Du JB, Liu XQ, Jin HF.   +6 more
europepmc   +2 more sources

Fear conditioning as a pathogenic mechanism in the postural tachycardia syndrome. [PDF]

Brain, 2022
Despite its increasing recognition and extensive research, there is no unifying hypothesis on the pathophysiology of the postural tachycardia syndrome.
Norcliffe-Kaufmann L, Palma JA, Martinez J, Camargo C, Kaufmann H.   +4 more
europepmc   +2 more sources

Neurovisceral phenotypes in the expression of psychiatric symptoms [PDF]

Frontiers in Neuroscience, 2015
This review explores the proposal that vulnerability to psychological symptoms, particularly anxiety, originates in constitutional differences in the control of bodily state, exemplified by a set of conditions that include Joint Hypermobility, Postural ...
Jessica Anne Eccles, Jessica Anne Eccles, Andrew Paul Owens, Andrew Paul Owens, Christopher J Mathias, Christopher J Mathias, Satoshi eUmeda, Hugo D Critchley, Hugo D Critchley, Hugo D Critchley   +9 more
doaj   +5 more sources

Network autonomic analysis of post-acute sequelae of COVID-19 and postural tachycardia syndrome. [PDF]

Neurol Sci, 2022
The autonomic nervous system (ANS) is a complex network where sympathetic and parasympathetic domains interact inside and outside of the network.
Novak P, Giannetti MP, Weller E, Hamilton MJ, Mukerji SS, Alabsi HS, Systrom D, Marciano SP, Felsenstein D, Mullally WJ, Pilgrim DM, Castells M.   +11 more
europepmc   +2 more sources

Orthostatic intolerance with tachycardia (postural tachycardia syndrome) and without (hypocapnic cerebral hypoperfusion) represent a spectrum of the same disorder. [PDF]

Front Neurol
Background Spectrum of chronic orthostatic intolerance without orthostatic hypotension includes postural tachycardia syndrome (POTS), with orthostatic tachycardia and hypocapnic cerebral hypoperfusion (HYCH), without orthostatic tachycardia.
Novak P, Systrom DM, Witte A, Marciano SP.   +3 more
europepmc   +2 more sources

Low-level tragus stimulation improves autoantibody-induced hyperadrenergic postural tachycardia syndrome in rabbits. [PDF]

Heart Rhythm O2, 2023
Background Recent studies have demonstrated that antiadrenergic autoantibodies are involved in the pathophysiology of postural orthostatic tachycardia syndrome (POTS). Objective The purpose of this study was to test the hypothesis that transcutaneous low-
Guo Y, Li H, Deng J, Zhang G, Fischer H, Stavrakis S, Yu X.   +6 more
europepmc   +2 more sources

Hyperadrenergic Postural Tachycardia Syndrome: Clinical Biomarkers and Response to Guanfacine. [PDF]

Hypertension
BACKGROUND: A subset of patients with postural tachycardia syndrome (POTS) are thought to have a primary hyperadrenergic cause. We assessed clinical biomarkers to identify those that would benefit from sympatholytic therapy.
Okamoto LE, Urechie V, Rigo S, Abner JJ, Giesecke M, Muldowney JAS, Furlan R, Shibao CA, Shirey-Rice JK, Pulley JM, Diedrich A, Biaggioni I.   +11 more
europepmc   +2 more sources