Results 51 to 60 of about 250,717 (298)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Short rehabilitation training program may improve postural control in children with autism spectrum disorders: preliminary evidences [PDF]

, 2020
Simona Caldani, Paola Atzori, Hugo Peyre, Richard Delorme, Maria Pia Bucci   +4 more
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Fallskip^® Parameters and Their Relationship with the Risk of Falls in Older Individuals with and Without Diabetes

Geriatrics
Background/Objectives: the assessment and prevention of fall risk is an essential component of healthcare, particularly for vulnerable populations such as older adults with or without diabetes.
Azahar Castillo-Montesinos, Lorenzo Brognara, Alejandra Mafla-España, Omar Cauli   +3 more
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

POSTURE AND ANAESTHESIA [PDF]

Survey of Anesthesiology, 1960
The effects of posture on respiration may include changes in pulmonary blood volume, changes in the compliance of the lungs, changes in the intrapulmonarv distribution of the inspired air, and limitations in the expansion of the lungs from simple mechanical interference with the normal diaphragmatic movement, the lateral expansion of the chest, and the
openaire   +2 more sources

Effects of downsizing care on the children and staff in a medical institution for disabled children after it was rebuilt

Japan Architectural Review, 2020
This study clarifies the impact of changes in the physical environment and the introduction of downsizing care in a medical institution for disabled children.
Kenji Suzuki, Hiroki Yamawaki
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Okulöncesi Otizmli Çocukların Postür ve Yürüyüş Özelliklerinin Akranları ile Karşılaştırılması

Ergoterapi ve Rehabilitasyon Dergisi
Amaç: Otizm spektrum bozukluğu (OSB) olan okulöncesi çocukların postür ve yürüyüş bozukluklarını inceleyerek OSB’li olmayan akranlarıyla karşılaştırmaktır. Gereç ve Yöntem: Çalışmaya 15 OSB’li ve 10 OSB’li olmayan, 4-7 yaş arasında çocuk dahil edilmiştir.
Fisun Yanardağ
doaj   +1 more source