Results 191 to 200 of about 100,974 (304)

Enhanced peripheral blood mononuclear cell lipid metabolism drives poor immunotherapy response via ferroptotic stress‐induced T cell exhaustion in hepatocellular carcinoma

open access: yesInterdisciplinary Medicine, EarlyView.
Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu   +6 more
wiley   +1 more source

Serum Apelin‐13 and Galectin‐3 in COVID‐19: Associations With Routine Biochemical Parameters and Diagnostic Performance in a Case–Control Study

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Serum Apelin‐13 and Galectin‐3 levels were measured by ELISA in COVID‐19–positive patients and controls and evaluated alongside routine biochemical parameters. COVID‐19 patients showed significant alterations in liver, renal, inflammatory, and metabolic markers.
İsmail Uğurlu
wiley   +1 more source

Effects of Summer Heat Stress on Physiological Parameters and Reproductive Efficiency of Barbarine Ewes Under Natural Outdoor or Indoor Conditions

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Climate change and rising ambient temperatures increasingly challenge sheep production systems in arid and semi‐arid regions, particularly during the summer breeding season. This study evaluated the effects of heat stress and direct solar exposure on physiological responses, metabolic profile, and reproductive performance of Barbarine ewes, a ...
Samia Khnissi   +4 more
wiley   +1 more source

Optimising Sulphur Fertilisation in Ryegrass–White Clover Swards Reduces Leached Nitrate Nitrogen Losses, While Increasing Plant Yield and Nitrogen Off‐Take

open access: yesJournal of Plant Nutrition and Soil Science, EarlyView.
The inclusion of sulphur at two inorganic nitrogen rates (0 and 150 kg N ha−1) improves plant productivity in a ryegrass–white clover sward and reduces nitrate‐N loss to groundwater in a free‐draining sandy loam soil. ABSTRACT Background Reducing nitrogen (N) losses to water, lessening reliance on inorganic fertiliser and maintaining agricultural ...
Donal Kinsella   +2 more
wiley   +1 more source

Renal NHE3 is required to limit hypokalemia and metabolic acidosis during dietary potassium deficiency. [PDF]

open access: yesPflugers Arch
Nogueira Coelho J   +7 more
europepmc   +1 more source

Nutritional adequacy and diet diversity following a tube weaning program

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Limited research has examined nutritional changes following tube weaning. The main objective of this study was to investigate the adequacy and quality of nutrition, growth, and gastrointestinal symptoms in children undergoing a 3‐week outpatient tube weaning program based on hunger provocation.
Maisa Keski‐Kuha   +5 more
wiley   +1 more source

Fermentation characteristics of four southern sichuan citrus cultivars

open access: yesJSFA reports, EarlyView.
Abstract Background Sichuan, China's leading citrus‐producing region has strong potential for citrus wine development. Citrus is rich in bioactive compounds that enhance flavor and health value, yet current citrus wines often show weak aroma and bitterness.
Zhiqing Zheng   +9 more
wiley   +1 more source

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