Results 131 to 140 of about 691,706 (351)

Targeted Penetrating Motif Engineering of BH3 Mimetic: Harnessing Non‐Canonical Amino Acids for Coinhibition of MCL‐1 and BCL‐xL in Acute Myeloid Leukemia

open access: yesAdvanced Science, EarlyView.
A structure‐guided peptide derived from a non‐canonical amino acid library simultaneously targets MCL‐1 and BCL‐xL to overcome apoptotic resistance in acute myeloid leukemia. Fused with a CXCR4‐binding motif, the engineered peptide exhibits selective intracellular delivery and potent in vivo efficacy, offering a promising therapeutic strategy against ...
Zhe Wang   +11 more
wiley   +1 more source

Subgenome Dominance in Allotetraploid Actinidia valvata Regulates RNA m6A Modification for Waterlogging Tolerance

open access: yesAdvanced Science, EarlyView.
The waterlogging tolerance of allotetraploid Actinidia valvata is inherited from one of its diploid progenitors, which leads to subgenome expression dominance, mediated by complex mechanisms including altered chromatin accessibility and DNA methylation.
Xiaoli Hu   +14 more
wiley   +1 more source

Searching for crop characteristics correlated with nitrogen efficiency in potato [PDF]

open access: yes, 2010
Breeders lack knowledge about genetic variation in nitrogen response of potato under low-input conditions and about relevant crop traits associated with variation in nitrogen efficiency.
Lammerts van Bueren, E.T.   +2 more
core  

In Situ Electrically Resettable Field‐Effect Transistor Biosensors for Continuous and Multiplexed Neurotransmitter Detection

open access: yesAdvanced Science, EarlyView.
The research team integrated a potentiometrically controlled pH electrode with carbon nanotube (CNT) field‐effect transistor (FET) biosensors on a single chip using compatible processes. By employing zonal modification and optimized pH‐sensitive probes, they achieved simultaneous quadruple‐target detection and tenfold reusability under physiological ...
Bo Xiao   +6 more
wiley   +1 more source

A Generative AI‐Assisted Piezo‐MEMS Ultrasound Device for Plant Dehydration Monitoring

open access: yesAdvanced Science, EarlyView.
This study introduces a complementary metal–oxide–semiconductor (CMOS)‐compatible wearable piezoelectric micromachined ultrasound transducers (PMUTs) that sandwiches the leaf (PMUT–Leaf–PMUT, PLP) and employs generative artificial intelligence for real‐time analysis.
Kaustav Roy   +7 more
wiley   +1 more source

Promiscuous potato: elucidating genetic identity and the complex genetic relationships of a cultivated potato germplasm collection

open access: yesFrontiers in Plant Science
A total of 3,860 accessions from the global in trust clonal potato germplasm collection w3ere genotyped with the Illumina Infinium SolCAP V2 12K potato SNP array to evaluate genetic diversity and population structure within the potato germplasm ...
Noelle L. Anglin   +15 more
doaj   +1 more source

Research on local seed potato value chain gaps and bottlenecks in Tajikistan. Potato production support and research to improve food security in Khatlon, Tajikistan [PDF]

open access: yes, 2016
This study examines potato value chains and recommends the promotion of potato as a tool for improving diets and decreasing child malnutrition. It is necessary to ensure that farmers have access to quality seed, fertilizers and pesticides, as well as ...
International Potato Center
core  

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