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Ranking of carcinogenic potency using a relative potency approach
Archives of Environmental Contamination and Toxicology, 1991Protocols for long-term carcinogen bioassays have become highly refined. The ability to interpret these bioassay results beyond the experimental setting, however, has not improved commensurately. As a consequence, society is still faced with the fact that data derived in these bioassays reflect highly specific experimental conditions which are vastly ...
L R, Glass +3 more
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Dissimilar dosing with high-potency and low-potency neuroleptics
American Journal of Psychiatry, 1984The authors studied high-potency versus low-potency neuroleptic dosing practices for 110 Boston-area psychiatric inpatients and compared the findings with the dosing practices reported in surveys of nearly 16,000 Veterans Administration patients.
R J, Baldessarini, B, Katz, P, Cotton
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Potencies of oral contraceptives
American Journal of Obstetrics and Gynecology, 1976Oral contraceptives are combinations of estrogens and progestogens or, in the case of the mini-pills, progestogens alone. With specific test procedures in laboratory animals or human subjects, it is possible to assign potency evaluations to the components relative to the progestational, estrogenic, or antiestrogenic activities of the progestogen or to ...
R A, Edgren, F M, Sturtevant
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Urethrectomy with Preservation of Potency
Journal of Urology, 1990Recent understanding of the anatomy of the pelvic plexus and cavernous nerves to the penis has resulted in modified surgical techniques of radical prostatectomy and radical cystoprostatectomy that allow for preservation of potency in the majority of men undergoing these procedures.
C B, Brendler, P N, Schlegel, P C, Walsh
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Potency of Parenteral Vitamin A
Nature, 1960VITAMIN A is widely employed in clinical practice and is also used extensively as a teratogenic agent for the production and study of fœtal abnormalities in laboratory animals1.
J W, MILLEN, D H, WOOLLAM
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Vaccines and their transfection potency
Vaccine, 1999Viral vaccines have been shown to contain residual host cell-DNA. There is no doubt about uptake and expression of foreign DNA in mammalian cells but the mechanism of transfection is not completely understood. It is suggested that DNA associates with several compounds and is transferred into the cell by endocytosis.
S, Gonser, J, Stalder, G, Folkers
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Halogenation and Anesthetic Potency
Survey of Anesthesiology, 1989Previous studies have shown that the anesthetic potency of organic compounds increases as a given halogen is replaced with successively larger halogens. These studies often are limited in the accuracy of determination of potency, rarely correlate potency with physical properties, and usually fail to include ether compounds.
A G, Targ +6 more
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Glucocorticoid potency and parachor
Journal of Steroid Biochemistry, 1976Abstract The potencies of some glucocorticoids by several assay methods show some interesting correlations with their parachors. Parachor is an additive and constitutive property of a molecule and is related to the molar volume and the surface tension.
P, Ahmad, A, Mellors
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Potency and pharmacokinetics of gestagens
Contraception, 1990Serum concentrations of gestagens were compared after single doses and after multiple doses (steady-state conditions) of four widely used oral contraceptives containing norethisterone (NET), levonorgestrel (LNG), desogestrel (DSG) and gestodene (GSD). There were marked differences among the gestagens with respect to the serum concentrations.
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Radioprotective Potency of Nanoceria
Current RadiopharmaceuticalsAbstract: Cancer presents a significant medical challenge that requires effective management. Current cancer treatment options, such as chemotherapy, targeted therapy, radiotherapy, and immunotherapy, have limitations in terms of their efficacy and the potential harm they can cause to normal tissues.
Maryam, Alvandi +3 more
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