Results 91 to 100 of about 12,864,594 (255)

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Effect of humidity and temperature on the potential-induced degradation

open access: yes, 2022
S.173-179This paper focusses on the physical conditions for a degradation mechanism of photovoltaic modules, known as potential-induced degradation. The analysis was made on several levels.
Köhl, Michael, Hoffmann, Stephan
core   +1 more source

Unveiling the Potential of Infrared Thermography in Quantitative Investigation of Potential-Induced Degradation in Crystalline Silicon PV Module

open access: yesSolar Energy Advances
Potential-induced degradation-shunting (PID-s) is a severe degradation mechanism in photovoltaic (PV) cells that significantly impacts module performance.
Ravi Kumar   +2 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

PML isoforms in response to arsenic: high-resolution analysis of PML body structure and degradation [PDF]

open access: yes, 2014
Arsenic is a clinically effective treatment for acute promyelocytic leukaemia (APL) in which the promyelocytic leukaemia (PML) protein is fused to retinoic receptor alpha (RARα).
Hands, K.J.   +7 more
core   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Optical Control of Small Molecule-Induced Protein Degradation [PDF]

open access: yes, 2019
As an emerging approach to protein perturbation, small molecule-induced protein degradation has gained significant attention as both a chemical tool and a potential therapeutic.
Alexander, Deiters   +2 more
core   +2 more sources

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