Results 21 to 30 of about 43,718 (173)

Neutrophil‐Mimetic Nanoscavengers Target the Inflammatory Microenvironment to Eliminate NETs/ROS and Immunomodulate cGAS‐STING Signaling in Septic AKI

Advanced Science, EarlyView.
Sepsis‐associated acute kidney injury is driven by oxidative stress, NETs overproduction, and dysregulated innate immunity. Here, we develop neutrophil‐mimetic nanoscavengers that integrate ROS‐scavenging Mn3O4 nanozymes with DNase‐1‐mediated NETs degradation to suppress cGAS‐STING signaling, reprogram macrophage polarization, and effectively alleviate
Zening Zhang, Chenxi Zhang, Ranran Luo, Qiuchi Wu, Pengchen Ren, Xinyu Liu, Yingying Luo, Zhongsheng Xu, Xiaojing He, Yun Liu   +9 more
wiley   +1 more source

A Hydraulic Approach to Equilibria of Resource Selection Games

, 2016
Drawing intuition from a (physical) hydraulic system, we present a novel framework, constructively showing the existence of a strong Nash equilibrium in resource selection games (i.e., asymmetric singleton congestion games) with nonatomic players, the ...
Gonczarowski, Yannai A., Tennenholtz, Moshe   +1 more
core   +1 more source

Short‐Term Scheduling Optimization of a Single‐Pipeline Refining System With High Melting Point Crude Oil

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT In order to reflect the actual production situation more comprehensively and optimize the production cost, this paper solves the short‐term scheduling optimization problem for a single pipeline containing high melting point crude oil. Based on the refining plan given by the upper layer, a multi‐objective optimization model with high melting ...
Jing Yao, Xianxin Liu, Zhen Pan, Chengming Hao, Xiangwei Xu, Wei Jia   +5 more
wiley   +1 more source

Matroids are Immune to Braess Paradox [PDF]

, 2017
The famous Braess paradox describes the following phenomenon: It might happen that the improvement of resources, like building a new street within a congested network, may in fact lead to larger costs for the players in an equilibrium.
Fujishige, Satoru, Goemans, Michel X., Harks, Tobias, Peis, Britta, Zenklusen, Rico   +4 more
core   +2 more sources

Development of a framework for implementing digital serious games in anatomy education: A single‐centre qualitative study

Anatomical Sciences Education, EarlyView.
Abstract Serious games are emerging as innovative tools in medical education, yet their adoption in anatomy teaching remains limited due to educator hesitancy, institutional constraints, and design challenges. This qualitative study explores the perspectives of anatomy educators on digital serious games and proposes a framework for their implementation.
Arthur Chin Haeng Lau, James Pickering
wiley   +1 more source

Prescribing competence: The pros and cons of different methods for assessment

British Journal of Clinical Pharmacology, EarlyView.
Evaluating a medical graduate’s competence in rational prescribing is challenging. With the aim to guide and inspire teachers, this narrative review explores different methods that can be used to assess prescribing competence. Each method has its own advantages and disadvantages, and thus a mix of different assessment methods is needed throughout the ...
David J. Brinkman, Erik M. Donker, Jelle Tichelaar, on behalf of the CP4T programme   +3 more
wiley   +1 more source

Connecting Industry 4.0, Servitisation and Sustainability: Territorial Implications for Global Value Chains

Business Strategy and the Environment, EarlyView.
ABSTRACT Globalisation has deepened the integration of international production within global value chains (GVCs), where the various stages of the manufacturing process are dispersed across countries. In today's volatile business environment, characterised by rapid technological advances (Industry 4.0) and evolving consumer preferences towards use ...
Javier Bilbao‐Ubillos, Vicente Camino‐Beldarrain, Gurutze Intxaurburu‐Clemente, Eva Velasco‐Balmaseda   +3 more
wiley   +1 more source

Congestion games with load-dependent failures: identical resources [PDF]

, 2009
We define a new class of games---congestion games with load-dependent failures (CGLFs). In a CGLF each player can choose a subset of a set of available resources in order to try and perform his task.
Penn, Michal, Polukarov, Maria, Tennenholtz, Moshe   +2 more
core   +1 more source

Bridging Theory and Prediction: A Hybrid SEM and Machine Learning Approach to Optimize Lean Construction for Megaproject Sustainability in China

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Construction megaprojects, large‐scale, complex, and capital‐intensive, are particularly prone to inefficiencies, cost overruns, delays, and environmental degradation due to fragmented workflows, stakeholder misalignment, and resource intensity.
Abdelazim Ibrahim, Tarek Zayed, Zoubeir Lafhaj, Ahmed Maged, Ahmed Farouk Kineber, Jingchao Yang   +5 more
wiley   +1 more source

Are physical performance and injury risk in a professional soccer team in match-play affected over a prolonged period of fixture congestion? [PDF]

, 2011
In this study, the effects of a prolonged period of fixture congestion (8 successive official matches in 26-days) on physical performance and injury risk and severity in a professional soccer team were investigated.
Carling, C., Dupont, G., Le Gall, F.,
core   +1 more source