Pulse characteristics of silicon double barrier optical sensors with signal amplification [PDF]
The pulse characteristics of optical sensors with double potential barriers formed on the opposite sides of a high-resistivity (v) silicon substrate have been studied. The first barrier is formed by multiple micro-sized Ti–vSi contact barriers surrounded
OLEKSANDR MALIK +2 more
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Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz +9 more
wiley +1 more source
Clinical Validation of Plasma p‐217tau in Neurological Diseases
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi +13 more
wiley +1 more source
Estimation of redistribution of potential in three-barrier structure
An experimental–computational method is proposed for determining the voltage drops across each junction of a three-barrier structure. The current–voltage characteristics of the blocking junctions are analyzed, and the asymmetries observed in experiments ...
A. V. Karimov +3 more
doaj
A dugong research strategy for the Great Barrier Reef World Heritage Area and Hervey Bay
A coordinated research strategy was developed in response to a request from a task force set up to implement decisions of the Great Barrier Reef Ministerial Council in relation to the conservation of dugongs in the Great Barrier Reef Region from ...
Oliver, J., Berkelmans, R.
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Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source
Gene Composition as a Potential Barrier to Large Recombinations in the Bacterial Pathogen Klebsiella pneumoniae. [PDF]
Comandatore F +11 more
europepmc +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Technical information sheet 9: New coastal areas of the Great Barrier Reef Marine Park
In January 1999, the Commonwealth Minister for the Environment and Heritage announced that certain coastal areas previously excluded from the Great Barrier Reef Marine Park would now be included.
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