Results 231 to 240 of about 9,094,493 (295)

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

MaxEnt Modeling of the Impacts of Human Activities and Climate Change on the Potential Distribution of <i>Plantago</i> in China. [PDF]

Biology (Basel)
Liao D, Zhou B, Xiao H, Zhang Y, Zhang S, Su Q, Yan X.   +6 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Exploration of the distribution and host range of <i>Phloeosinus deleoni</i> Blackman (Curculionidae, Scolytinae) through collection records, field collections and modelling of potential distribution. [PDF]

Biodivers Data J
Cervantes-Espinoza M, Maya-Ramos JL, Atkinson T, Ruíz EA, Armendariz-Toledano F.   +4 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Predicting the potential distribution of <i>Phacellanthus tubiflorus</i> (Orobanchaceae): a modeling approach using MaxEnt and ArcGIS. [PDF]

PeerJ
Chang C, Cai F, Shen L, Jia X, Liu Z, Wang C, Fu Y, Luo Y.   +7 more
europepmc   +1 more source

Potential Distribution of Tribe Erythroneurini in China Based on the R-Optimized MaxEnt Model, with Implications for Management. [PDF]

Insects
Yuan X, Ran W, Xu W, Zhao Y, Su D, Song Y.   +5 more
europepmc   +1 more source

Exploring Potential Distribution and Environmental Preferences of Three Species of <i>Dicranomyia</i> (Diptera: Limoniidae: Limoniinae) Across the Western Palaearctic Realm Using Maxent. [PDF]

Insects
Ciliberti P, Starkevich P, Podenas S.
europepmc   +1 more source

Predicting the Potential Distribution of Cheirotonus jansoni (Coleoptera: Scarabaeidae) Under Climate Change. [PDF]

Insects
Yu Y, Li Z.
europepmc   +1 more source