Results 91 to 100 of about 1,366,103 (300)

Potential energy curves in proton transfer reactions [PDF]

open access: yesProceedings of the Royal Society of London. Series A. Mathematical and Physical Sciences, 1940
The potential energy curves involved in proton transfer reactions are discussed, with special reference to the base-catalysed prototropy of ketones. The assumption of covalent binding throughout is inadequate to account in detail for the relations observed between basic strength and catalytic power.
openaire   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

A Methodology for Constructing Marginal Abatement Cost Curves for Climate Action in Cities

open access: yesEnergies, 2016
As drivers of climate action, cities are taking measures to reduce greenhouse gas (GHG) emissions, which if left unabated pose a challenge to meeting long-term climate targets.
Nadine Ibrahim, Christopher Kennedy
doaj   +1 more source

The three-center two-positron bond. [PDF]

open access: yesChem Sci, 2022
Charry J   +6 more
europepmc   +1 more source

Embedded density functional theory for covalently bonded and strongly interacting subsystems [PDF]

open access: yes, 2011
Embedded density functional theory (e-DFT) is used to describe the electronic structure of strongly interacting molecular subsystems. We present a general implementation of the Exact Embedding (EE) method [J. Chem. Phys.
Barnes, Taylor A.   +2 more
core  

Grid-based density functional calculation of many-electron systems

open access: yes, 2010
Exploratory variational pseudopotential density functional calculations are performed for the electronic properties of many-electron systems in the 3D cartesian coordinate grid (CCG). The atom-centered localized gaussian basis set, electronic density and
Afeefy   +35 more
core   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

Novel Quantification Method of Aggregated Energy Flexibility Based on Power-Duration Curves

open access: yesIEEE Access
Energy flexibility aggregation is an emerging concept regarded as a potential solution to the challenges of integrating distributed renewable energy sources. For aggregators to make informed decisions on how to utilise the energy flexibility of prosumers
Freddy Plaum   +2 more
doaj   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Advancing Industrial Process Electrification and Heat Pump Integration with New Exergy Pinch Analysis Targeting Techniques

open access: yesEnergies
The process integration and electrification concept has significant potential to support the industrial transition to low- and net-zero-carbon process heating.
Timothy Gordon Walmsley   +3 more
doaj   +1 more source

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