Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Comparative Analysis of Gastrointestinal Microbiota Along the Digestive Tract in Sika Deer and Reindeer and Prediction of Their Potential Function. [PDF]
Peng X, Han H, Hu R, Kong F, Lu Y.
europepmc +1 more source
Diversity and potential function of pig gut DNA viruses. [PDF]
Qin J +8 more
europepmc +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Production function approach to calculating potential growth and output gaps - estimates for the EU Member States and the US [PDF]
This paper describes the methodology for calculating potential growth and output gaps using a production function approach. On the basis of the Commission services Spring 2002 economic forecasts, the approach is illustrated by providing estimates for the
Werner R�ger +2 more
core
Potential function of miRNA as a diagnostic biomarker for human ovarian cancer. [PDF]
Liu F, An Z, Tang C, Han X.
europepmc +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Potential-function-based Analysis of an off-line Heap Construction Algorithm [PDF]
Roberts, A, Symvonis, A
core
Integrated analysis of ARHGAP6 potential function and prognostic value in acute myeloid leukemia. [PDF]
Yang D, Li Y, Ma P, Xiao F.
europepmc +1 more source
Circular RNA profile in Graves' disease and potential function of hsa_circ_0090364. [PDF]
Jiang Z +7 more
europepmc +1 more source

