Results 191 to 200 of about 4,745,445 (215)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Systematic characterization of Gossypium GLN family genes reveals a potential function of GhGLN1.1a regulates nitrogen use efficiency in cotton. [PDF]

open access: yesBMC Plant Biol
Li X   +13 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source
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Effects of cancer chemotherapy on gonadal function and reproductivecapacity

Ca-A Cancer Journal for Clinicians, 1990
H E Averette, Hervy E Averette
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Self‐consistent molecular orbital methods 25. Supplementary functions for Gaussian basis sets

Journal of Chemical Physics, 1984
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Combining Wave Function Methods with Density Functional Theory for Excited States

Chemical Reviews, 2018
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Mutant phenotypes for thousands of bacterial genes of unknown function

Nature, 2018
Ryan A Melnyk   +2 more
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