Results 101 to 110 of about 1,786,583 (270)

Physics and optimization of beta-beams: From low to very high gamma

open access: yes, 2006
The physics potential of beta beams is investigated from low to very high gamma values and it is compared to superbeams and neutrino factories. The gamma factor and the baseline are treated as continuous variables in the optimization of the beta beam ...
J. Bouchez   +6 more
core   +1 more source

Potential impact of sodium glucose co-transporter (SGLT2) inhibitors on cholesterol fractions in stage 3 chronic kidney disease

open access: yesThe Egyptian Journal of Internal Medicine
Abstract Introduction Data on sodium glucose co-transporter 2 inhibitors impact on lipids in patients with diabetes are available and only a handful of studies have explored this effect in individuals with both diabetes and renal impairment; lipid parameters were not the primary focus of those earlier studies.
Rabab Mahmoud Ahmed   +3 more
openaire   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Post-impact damage tolerance of natural fibre-reinforced sheet moulding compound

open access: yesAdvanced Composites Letters, 2020
Natural fibre composites are of interest for a wide range of semi-structural applications in the building, construction and automotive sector. For a number of these applications, the evaluation of performance degradation after impact is of some relevance.
Harish K Patel, Ton Peijs
doaj   +1 more source

EcoBlock: Grid Impacts, Scaling, and Resilience [PDF]

open access: yes, 2017
Widespread deployment of EcoBlocks has the potential to transform today's electricity system into one that is more resilient, flexible, efficient and sustainable.
Bariya, Mohini   +3 more
core  

Simulating X-ray Supercavities and Their Impact on Galaxy Clusters

open access: yes, 2010
Recent X-ray observations of hot gas in the galaxy cluster MS 0735.6+7421 reveal huge radio-bright, quasi-bipolar X-ray cavities having a total energy ~10^{62} ergs, the most energetic AGN outburst currently known.
Baldi   +27 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Impact of high-risk sex and focused interventions in heterosexual HIV epidemics: a systematic review of mathematical models.

open access: yesPLoS ONE, 2012
BackgroundThe core-group theory of sexually transmitted infections suggests that targeting prevention to high-risk groups (HRG) could be very effective.
Sharmistha Mishra   +4 more
doaj   +1 more source

The impact of Stellar feedback from velocity-dependent ionised gas maps. -- A MUSE view of Haro 11

open access: yes, 2019
We have used the capability of the MUSE instrument to explore the impact of stellar feedback at large scales in Haro 11, a galaxy under extreme starburst condition and one of the first galaxies where Lyman continuum (LyC) has been detected.
Adamo, A.   +8 more
core   +1 more source

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