Results 161 to 170 of about 12,864,962 (300)

Development of High-Efficiency Mitochondrial Protease Targeting Chimeras (MtPTACs) for Targeted Degradation of POLRMT and Beyond. [PDF]

open access: yesJACS Au
Chen C   +15 more
europepmc   +1 more source

Local Knowledge and Natural Resource Management in a Peasant Farming Community Facing Rapid Change: A Critical Examination [PDF]

open access: yes
Environmental degradation is a major global problem, and addressing it is a key Millennium Development Goal. Its impacts are not just environmental (e.g., species loss), but also economic (e.g., reduced agricultural productivity), with degradation ...
Jules R Siedenburg
core  

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Visualizing a Li-Depleted Amorphous Cathode-Electrolyte Interphase in Sulfide Solid-State Batteries Using In Situ Cryogenic Electron Microscopy. [PDF]

open access: yesAdv Sci (Weinh)
Nomura Y   +10 more
europepmc   +1 more source

Equity Issues Relating to Irrigation-induced Soil Degradation under Left Bank Canal of Tungabhadra Project Area, Karnataka [PDF]

open access: yes
The equity issues concerning soil degradation and soil reclamation have been analysed for Tungabhadra Project Area of the Karnataka state. The study is based on primary data obtained from 325 respondent farmers.
Nagaraj, N., Chinnappa, B.
core  

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

open access: yesFEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Home - About - Disclaimer - Privacy