Results 121 to 130 of about 33,669,679 (309)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Retraction Note: Optical rectification and absorption coefficients studied by a short-range topless exponential potential well with inverse square root. [PDF]
Sci Rep, 2020 Yu Q, Guo K, Hu M.
europepmc +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Techne, 2012 One-dimensional square potential well is used as a model for quantum dots. Its Schroedinger's equations and their solutions both eigenstates and eigenenergies for he lowest three levels are explained qualitatively and derived mathematically.
Liek Wilardjo
doaj
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Generalized Heisenberg Algebras, SUSYQM and Degeneracies: Infinite Well and Morse Potential
Symmetry, Integrability and Geometry: Methods and Applications, 2011 We consider classical and quantum one and two-dimensional systems with ladder operators that satisfy generalized Heisenberg algebras. In the classical case, this construction is related to the existence of closed trajectories.
Véronique Hussin, Ian Marquette
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Optimization of conveyance of quantum particles by moving potential well
Physical Review ResearchQuantum mechanical control of the position of a particle by using a trapping potential well is an important problem for the manipulation of a quantum particle.
Satoshi Morita +2 more
doaj +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source