Results 71 to 80 of about 2,210,830 (305)
An Empirical Model of Demand for Future Health States when Valuing Risk-Mitigating Programs [PDF]
, 2004 51 p.We develop a structural option price model in which individuals choose among competing risk-mitigating programs to alter their probability of experiencing future years in various degraded health states.
Cameron, Trudy Ann, DeShazo, J. R.
core
The Potential Impact of the Great Recession on Future Retirement Incomes [PDF]
, 2011 Estimates the effects of job loss, slower wage growth, and withdrawals from retirement savings during the 2007-09 recession on retirement incomes at age 70, including decline in income by age group and number of those likely to live in poverty at ...
Barbara A. Butrica +2 more
core +2 more sources
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Inequity in mortality rates and potential years of life lost caused by COVID-19 in the Greater Santiago, Chile. [PDF]
Sci Rep, 2023 Ayala A +4 more
europepmc +2 more sources
Mortality in England and Wales attributable to current alcohol consumption. [PDF]
, 2001 STUDY OBJECTIVE: To estimate the number of deaths attributable to current alcohol consumption levels in England and Wales by age and sex. DESIGN: Epidemiological approach using published relative risks and population data.
Britton, A, McPherson, K
core +4 more sources
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Croatian medical journal, 2002 To determine the leading causes of death that contribute most to premature mortality in Slovenia; to classify premature mortality according to the cause of death, age, and sex; and to determine the age point before which premature mortality becomes a potential loss to the society.Potential economic losses to society were estimated by use of years of ...
Jozica Selb, Semerl, Janja, Sesok
openaire +1 more source
Burden of smoking in Lithuania: attributable mortality and years of potential life lost [PDF]
European Journal of Public Health, 2017 High mortality rates from smoking related diseases are a significant public health issue in Lithuania. Study aims to estimate the number of smoking attributable deaths (SADs) and years of potential life lost in Lithuania in 2013.Gender, age and disease specific mortality was calculated by applying the smoking attributable fractions (SAFs) to prevalence
Vaida, Liutkute +3 more
openaire +2 more sources
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source