Results 121 to 130 of about 2,028,454 (299)

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

Engineered Allosteric Biosensor for In Situ DNA Glycosylase Detection in Neuroblastoma Risk Stratification and Drug Resistance Monitoring

Advanced Science, EarlyView.
An engineered allosteric biosensor (UUU‐DZ‐tFNA) was developed, in which UDG specifically recognizes and activates a DNAzyme to achieve signal cycle amplification in a sequentially activatable mode. UUU‐DZ‐tFNA achieves in situ UDG detection across multiple biological levels and facilitates risk stratification and drug resistance monitoring of NB ...
Yaqing Lu, Yingyu Zhang, Xianwei Zhang, Mengxin Zhang, Fei Zhang, Jushan Sun, Yahui Yang, Kangbo Liu, Peng Wang, Shuying Luo, Wancun Zhang   +10 more
wiley   +1 more source

Polypharmacy and Potentially Inappropriate Medication in Iranian People With Metabolic Syndrome: Epidemiological Aspects and Related Factors, a Multi‐Level Cross‐Sectional National Study

Health Science Reports
Background and Aims Polypharmacy, characterized by the concurrent use of five or more medications in a prescription, potentially resulting in adverse outcomes, is frequently observed among individuals with metabolic syndrome, which encompasses a ...
Mojdeh Daneshmand, Hamidreza Jamshidi, Mohammad‐Reza Malekpour, Erfan Ghasemi, Sahar Saeedi Moghaddam, Seyede Salehe Mortazavi, Mohsen Shati, Mohammad Hadi Farjoo, Farshad Farzadfar   +8 more
doaj   +1 more source

Prevalence and Predictors of Potentially Inappropriate Medications Among Patients Aged ≥65 Years on Hospital Admissions in Kuwait

Clinical Interventions in Aging, 2022
Hesah Alshammari, Eman Al-Saeed, Zamzam Ahmed, Zoe Aslanpour Department of Clinical and Pharmaceutical Sciences, School of Life and Medical Sciences, University of Hertfordshire, Hatfield, UKCorrespondence: Hesah Alshammari, Department of Clinical and ...
Alshammari H, Al-Saeed E, Ahmed Z, Aslanpour Z   +3 more
doaj  

An Expertise Transfer Framework For Autonomous Surgical Assistance

Advanced Science, EarlyView.
This study introduces an expertise transfer framework for procedure‐spanning autonomous surgical assistance. By emulating expert logic through hierarchical perception, attention modeling, and knowledge graph‐based decision‐making, the system provides near‐expert surgical view assistance.
Yuan Gao, Guangdi Chu, Wei Jiao, Yuchuan Zhong, Hang Yuan, Chengjun Li, Jinhua Li, Shuxin Wang, Bo Guan, Jianchang Zhao, Lizhi Pan, Haitao Niu, Jianmin Li   +12 more
wiley   +1 more source

Potentially inappropriate medication use among Brazilian elderly in a medication management program

Revista de Ciências Farmacêuticas Básica e Aplicada, 2016
A descriptive, cross-sectional study of data from 15 elderly users of the Medication Therapy Management (MTM) service, delivered as a university extension project at a primary health unit in the city of Minas Gerais, Brazil was carried out. The objective
Vanessa Mayra Oliveira Mauricio, Simone Araújo Medina Mendonça, Mariana Martins Gonzaga Nascimento, Djenane Ramalho de Oliveira   +3 more
doaj  

Trends over time and risk factors in inappropriate prescribing in older adults with multimorbidity and polypharmacy: a longitudinal secondary analysis of the OPERAM trial

Swiss Medical Weekly
  BACKGROUND AND AIM OF THE STUDY: Polypharmacy is common among older adults and associated with potentially inappropriate medications and potential prescribing omissions, which together constitute potentially inappropriate prescriptions, contributing
Jonathan Huschka, Katharina Tabea Jungo, Valerie Aponte Ribero, Lara Brockhus, Denis O’Mahony, Mary Randles, Sophie Marien, Clara Drenth, Anne Spinewine, Wilma Knol, Drahomir Aujesky, Nicolas Rodondi, Carole E. Aubert   +12 more
doaj   +1 more source

LLM‐Assisted Design of Ultralow‐κ$\kappa$ Chalcogenides

Advanced Science, EarlyView.
An AI assisted, physics guided workflow accelerates the discovery of ultralow thermal conductivity materials by combining Bayesian optimization, evidence conditioned LLM reasoning, and automated physics‐based validation. The framework uncovers dynamically stable Ag based chalcogenides with ultralow thermal conductivity and promising thermoelectric ...
Yujie Liu, Congran Jia, Yuzhou Hao, Xuejie Li, Yang Wang, Artem Oganov, Jun Sun, Xiangdong Ding, Turab Lookman, Zhibin Gao   +9 more
wiley   +1 more source

Potentially inappropriate medication usage, fall and comorbidities in geriatric patients diagnosed with chronic subdural hematoma

, 2021
Aim: The annual incidence of chronic subdural hematoma is 2-4/100000 in geriatric population. We aimed to investigate relationship between potentially inappropriate medication usage according to Beers 2019 criteria, fall and Charlson comorbidity index in
Gürkan, Gökhan, Saraç, Zeliha Fulden, Sevin, İsmail Ertan, Taşkıran, Emin   +3 more
core  

Symptom‐Driven Prediction of Chronic Multimorbidity with a Macro–Micro Heterogeneous Graph Neural Network

Advanced Science, EarlyView.
Clinical symptoms offer a window into multimorbidity. A macro‐micro heterogeneous graph neural network integrates clinical records with biomedical knowledge to improve patient‐level symptom‐disease association learning and visit‐level multimorbidity completion.
Yiheng Ye, Miaoru Han, Siqiao Tang, Zongxiang Zhang, Haichen Shen, Bingzhen Sun, Yan Zhang, Xiaodong Chu, Lijuan Deng, Chaoyang Zheng, Qingchun Huang, Kun Bao, Ronghua Zhang, Yong Wang, Fengwei Zhang, Xiaoli Chu   +15 more
wiley   +1 more source