Results 121 to 130 of about 1,873,177 (302)

Over-the-counter medications potentially inappropriate for the elderly [PDF]

Revista da Associação Médica Brasileira, 2018
Milton Luiz Gorzoni, Renato Moraes Alves Fabbri   +1 more
openaire   +3 more sources

Data-Driven Assessment of Potentially Inappropriate Medication in the Elderly

, 2018
Multimorbid patients taking polypharmacy represent a growing population at high risk for inappropriate prescribing. Various lists for identifying potentially inappropriate medication are spread across scientific journals and difficult to access. To address this ongoing need, a new database named PIMBase is developed which integrates these well-known ...
Friedrichs, Marcel, Shoshi, Alban, Kleine, Maren   +2 more
openaire   +2 more sources

SAT1‐Induced Spermidine Depletion Potentiates Food Allergy

Advanced Science, EarlyView.
Spermidine depletion, driven by upregulated spermidine/spermine N1‐acetyltransferase (SAT1), potentiates food allergy by promoting mast cell degranulation through autophagy suppression. SAT1 physically interacts with the long noncoding RNA Cdk19os to inhibit Atg5 and Atg7, disrupting autophagic flux.
Manman Liu, Beiyu Zhang, Junjuan Wang, Yue Jiang, Shiwen Han, Qianwei Wang, Lingyu Zeng, Jinfeng Wang, Huilian Che   +8 more
wiley   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

Prescription pattern and prevalence of potentially inappropriate medications among elderly patients in a Nigerian rural tertiary hospital

, 2013
Joseph O Fadare,1 Segun Matthew Agboola,2 Olumide Augustine Opeke,3 Rachel A Alabi41Department of Medical Pharmacology and Therapeutics, Obafemi Awolowo University, Ile-Ife, Nigeria; 2Department of Family Medicine, 3Department of Internal Medicine ...
Agboola SM, Opeke OA, Fadare JO, Alabi RA   +3 more
core  

Prevalence and Risk Factors of Potentially Inappropriate Medications at Discharge in Older Adults with Heart Failure: A Retrospective Pharmacovigilance Study

Prevalence and Risk Factors of Potentially Inappropriate Medications at Discharge in Older Adults with Heart ...
Jiang, Zhenhua
core   +1 more source

Engineered Allosteric Biosensor for In Situ DNA Glycosylase Detection in Neuroblastoma Risk Stratification and Drug Resistance Monitoring

Advanced Science, EarlyView.
An engineered allosteric biosensor (UUU‐DZ‐tFNA) was developed, in which UDG specifically recognizes and activates a DNAzyme to achieve signal cycle amplification in a sequentially activatable mode. UUU‐DZ‐tFNA achieves in situ UDG detection across multiple biological levels and facilitates risk stratification and drug resistance monitoring of NB ...
Yaqing Lu, Yingyu Zhang, Xianwei Zhang, Mengxin Zhang, Fei Zhang, Jushan Sun, Yahui Yang, Kangbo Liu, Peng Wang, Shuying Luo, Wancun Zhang   +10 more
wiley   +1 more source

An Expertise Transfer Framework For Autonomous Surgical Assistance

Advanced Science, EarlyView.
This study introduces an expertise transfer framework for procedure‐spanning autonomous surgical assistance. By emulating expert logic through hierarchical perception, attention modeling, and knowledge graph‐based decision‐making, the system provides near‐expert surgical view assistance.
Yuan Gao, Guangdi Chu, Wei Jiao, Yuchuan Zhong, Hang Yuan, Chengjun Li, Jinhua Li, Shuxin Wang, Bo Guan, Jianchang Zhao, Lizhi Pan, Haitao Niu, Jianmin Li   +12 more
wiley   +1 more source

Comparison of Potentially Inappropriate Medications for People with Dementia at Admission and Discharge during An Unplanned Admission to Hospital: Results from the SMS Dementia Study

, 2019
People with dementia (PWD) and cognitive impairment are particularly vulnerable to medication problems, and unplanned admission to hospital presents an opportunity to address polypharmacy, potentially inappropriate medications (PIMs) and anticholinergic ...
Anne Fullerton, John Attia, Ashley Kable, Kerrin Palazzi, On behalf of SMS Dementia Study investigators, Andrew Searles, Kim Edmunds, Samantha Fraser, Carolyn Hullick, Dimity Pond, Christopher Oldmeadow, Searles, A, Pond, D, Fullerton, A, Palazzi, K, Edmunds, K, Fraser, S, Oldmeadow, C, Hullick, C, Kable, A, Attia, J   +20 more
core   +2 more sources

Prevalence of polypharmacy: a cross-sectional study in Singapore public healthcare institutions

Singapore Medical Journal
Introduction: Polypharmacy is associated with increased prevalence of potentially inappropriate medications (PIMs), leading to higher risk of adverse drug events and medication errors.
Hui Wen Ho, BSc (Pharm), Leng Chuan Goh, BSc (Pharm), Jiun Yu Christina Tan, PharmD, Deborah Chia, MClinPharm, Jun Long Marvin Sim, MclinPharm, Jie Lin Soong, PharmD   +5 more
doaj   +1 more source