Results 241 to 250 of about 1,873,177 (302)

Benzodiazepines use in primary care England: Prescribing patterns and adverse consequences

British Journal of Clinical Pharmacology, EarlyView.
Aims Benzodiazepines (BZDs) are commonly prescribed for anxiety and insomnia but carry risks such as dependence, adverse drug reactions (ADRs) and mortality. Despite deprescribing efforts, the influence of recent prescribing trends, COVID‐19 and adverse outcomes on prescribing patterns in England remains uncertain.
Alvina Chaudhry, Muhammad Umair Khan, Barbara Conway, Syed Shahzad Hasan   +3 more
wiley   +1 more source

Development and validation of a machine-learning model for the risk of potentially inappropriate medications in elderly stroke patients. [PDF]

Front Pharmacol
Yang X, Ye Q, Zhang M, Xu Y, Yang M.
europepmc   +1 more source

Economic evaluations of antiobesity medications: A systematic literature review

British Journal of Clinical Pharmacology, EarlyView.
The global prevalence of obesity is rising rapidly. With several antiobesity medications approved and many more in development, understanding their economic value is increasingly important. This study reviews full economic evaluations of approved antiobesity medications to assess cost‐effectiveness and inform reimbursement and access decisions.
Martina Jurković, Almir Fajkić, Andrea Katrin Faour, Mirna Momčilović, Petra Turčić, Andrej Belančić   +5 more
wiley   +1 more source

Polypharmacy and Potentially Inappropriate Medications in Adults ≥75 Years of Age by Dementia and Frailty Status: The ARIC Study. [PDF]

Mayo Clin Proc
Lutsey PL, Misialek JR, Whitsel EA, Lakshminarayan K, Kucharska-Newton AM, Windham BG, Sullivan KJ, Secora A, Grams ME, Farley JF.   +9 more
europepmc   +1 more source

Practice‐level variation in potentially inappropriate prescribing in middle‐aged adults: A repeated cross‐sectional study in South London general practice

British Journal of Clinical Pharmacology, EarlyView.
Aim To quantify between‐practice variation in potentially inappropriate prescribing (PIP) among middle‐aged adults (45–64 years) in UK general practice, and to identify patient‐ and practice‐level characteristics associated with PIP. Methods Repeated cross‐sectional study using linked data from the Lambeth DataNet and Quality Outcomes Framework across ...
Ryan Jayesinghe, Amandeep Khatter, Stevo Durbaba, Mark Ashworth, Benjamin Jacob, Frank Moriarty, Patrick Redmond   +6 more
wiley   +1 more source

Polypharmacy, drug-drug interactions, and potentially inappropriate medications among older adults: a cross-sectional study in Northeast Ethiopia. [PDF]

Front Public Health
Endalifer BL, Kassa MT, Ejigu YW, Ambaye AS.   +3 more
europepmc   +1 more source

Population pharmacokinetics of levetiracetam in term neonates with hypoxic–ischemic encephalopathy and therapeutic hypothermia: The LEVNEONAT‐1 study

British Journal of Clinical Pharmacology, EarlyView.
Aim This study aimed to describe the pharmacokinetics (PK) of levetiracetam (LEV) in term neonates treated for neonatal seizures secondary to hypoxic–ischemic encephalopathy (HIE). Methods Fifteen neonates were included and received a loading dose ranging from 30 to 60 mg/kg followed by eight maintenance doses corresponding to one‐fourth of the loading
Léo Mimram, Moreno Ursino, Julie Leger, Emilie Bourrel‐Ponchel, Florence Flamein, Alexandra Chadie, Isabelle Guellec, Sarah Zohar, Vincent Jullien, Géraldine Favrais   +9 more
wiley   +1 more source

Characterizing patient portal use of people with cognitive impairment and potentially inappropriate medications. [PDF]

J Am Geriatr Soc
Green AR, Martin D, Jessen A, Wu MMJ, Daddato AE, Rosado RQ, Gleason KT, Wec A, Wolff JL, Taylor CO, Bayliss EA.   +10 more
europepmc   +1 more source

The prevalence and factors associated with potentially inappropriate medications in Chinese older outpatients with heart failure. [PDF]

BMC Geriatr
Zhang Y, Chen Z, Tian F.
europepmc   +1 more source