Results 121 to 130 of about 249,676 (252)
The translational pipeline of precision medicine in clinical oncology. Schematic overview of the individualized cancer care workflow. (1) Input: Patient samples undergo multi‐omic profiling via NGS, single‐cell diagnostics, spatial maps, and epigenetic sequencing.
Asif Jan +3 more
wiley +1 more source
ABSTRACT Ulcerative colitis (UC) is a chronic inflammatory disease of the colon with limited effectiveness and safety of current drug therapies. Betulinic acid (BA) is a naturally occurring pentacyclic triterpenoid present in traditional Chinese medicines used clinically as retention enemas for UC, but its direct effects and mechanisms remain unclear ...
Lina Dong +7 more
wiley +1 more source
Type IV Congenital Pouch Colon in Male Children: Anatomical Variations and a Proposed New Subclassification. [PDF]
Solanki S +4 more
europepmc +1 more source
Schisandrin C: A Dual Anti‐Colorectal Cancer Strategy Targeting PPARγ. ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer mortality, necessitating novel therapeutic strategies. Schisandrin C (SinC), a bioactive lignan from Schisandra chinensis, exhibits diverse pharmacological activities, but its anti‐CRC mechanisms are poorly ...
Xiao Wei +4 more
wiley +1 more source
The role of the host—Neutrophil biology
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Stimuli‐responsive nanostructured hydrogen sulfide donors for enhanced cancer treatments
Three typical kinds of stimuli‐responsive nanostructured hydrogen sulfide (H2S) donors are reviewed. The nanostructures ensure precise delivery of H2S to the lesion site and regulate the release behavior. The H2S‐based gas therapy has been used to synergize with other cancer treatment modalities, achieving enhanced efficacy while reducing side effects.
Yuxuan Lyu +7 more
wiley +1 more source
Abstract In this article, I analyze the co‐constitution of race and neoliberalism within the discourse of an English language classroom. Appealing to modernist/colonial histories of race and capital, I first examine how racial neoliberalism produces a normalized, unmarked subject‐position through the conflation of moral responsibility with human ...
Justin Lance Pannell
wiley +1 more source
Factors affecting the removal of grass seed foreign bodies in canine patients
Abstract Background Migrating grass seed foreign bodies (GSFBs) commonly cause pathology in canine patients. Anecdotally, antibiotic treatment eliminates the fluid pockets that usually form around GSFBs, complicating identification and retrieval. Methods Radiology reports tagged with ‘soft tissue foreign body’ were retrospectively analysed to identify ...
Charli M. Twyford, Conor Rowan
wiley +1 more source
Abstract Background South American camelids (SACs) have become increasingly popular in the UK. Consequently, knowledge among veterinary practitioners about diseases in these non‐native species has improved, although gaps remain. The remit of this study was to identify common diseases of SACs based on Animal and Plant Health Agency (APHA) surveillance ...
Sonja Jeckel +2 more
wiley +1 more source
Anorectal malformations in children
Background/Purpose: Anorectal malformations are one of the most common congenital defects. This study was undertaken to study the hospital incidence of anorectal malformations (ARM), frequency of various types of defects, their sex distribution and the ...
Bhargava Pranshu, Mahajan J, Kumar Ajay
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