Results 151 to 160 of about 249,676 (252)
Pouch colon malformation: Case report Kolonik pos anomalisi: Olgu sunumu
, 2000 Three patients with pouch colon malformation were treated surgically between 1995 and 1997. Babies presented with abdominal distention and bilious vomiting.
Boneval, C. +5 more
core
Targeting KRAS for cancer therapy
British Journal of Pharmacology, EarlyView.In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia +4 more
wiley +1 more source
Author Correction: Whole exome sequencing reveals rare variants linked to congenital pouch colon. [PDF]
Sci Rep, 2018 Mathur P +5 more
europepmc +1 more source
Assessment of Nutritional Status of Patients of Congenital Pouch Colon Following Definitive Surgery. [PDF]
J Indian Assoc Pediatr Surg, 2017 Al-Mendalawi MD.
europepmc +2 more sources
Long-term outcome after ileal pouch-anal anastomosis : function and health-related quality of life
, 2007 PURPOSE: This study was designed to investigate long-term pouch function and health-related quality of life in a single, large cohort of patients with ileal pouch-anal anastomosis for ulcerative colitis.
Lindholm, E +3 more
core
British Journal of Pharmacology, EarlyView.Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff +3 more
wiley +1 more source
Liquid Biopsy and Multi‐Cancer Early Detection Tests for Cancer Screening: A Scoping Review
Clinical Genetics, EarlyView.There is a large body of evidence on liquid biopsy and multi‐cancer detection tests for cancer screening. Most studies addressed test performance outcomes, while fewer addressed clinical outcomes, implementation, and cost‐effectiveness. No studies evaluated cancer mortality.
Tessa Robinson +6 more
wiley +1 more source
Cell Proliferation, EarlyView.The lichen‐derived metabolite methyl 4‐O‐demethylbarbatate (Me‐4‐O‐DBA) suppresses glioma stemness, motility, and metabolic plasticity through inhibition of HIF‐1α signaling and synergistically enhances temozolomide activity, highlighting a potential strategy to target stemness‐driven therapeutic resistance in glioma.
Rui Zhou +8 more
wiley +1 more source
Congenital Pouch Colon with Rectal Atresia: A Rare Association. [PDF]
J Neonatal Surg, 2016 Mirza B, Saleem M.
europepmc +1 more source
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aim To develop a next‐generation, longer‐acting, more‐clinical‐benefits agonist to achieve sustained efficacy with improved tolerability. Methods CT130 was designed from semaglutide. Binding affinity was validated via molecular dynamics and cellular assays.
Wei Ding +4 more
wiley +1 more source