Results 41 to 50 of about 8,316 (203)

A New Requirement for Publication: Access to Effective Drugs for Ethical Reasons, The Example of Heart Failure

ESC Heart Failure, 2021
The past decade has witnessed the publication of many trials in the field of heart failure, several of which have demonstrated that new drugs could potentially reduce major cardiac events and sometimes even decrease total mortality.
François Roubille, Nicolas Lamblin
doaj   +1 more source

Clinical profiles associated with rapidly progressive interstitial lung disease in antisynthetase syndrome: A multicentric cohort study (TYPASS study)

Journal of Internal Medicine, Volume 299, Issue 3, Page 365-380, March 2026.
Abstract Objectives To assess factors associated with rapidly progressive interstitial lung disease (ILD) (RP‐ILD) at time of ILD diagnosis in a multicentric retrospective cohort study of antisynthetase syndrome (ASyS). We used a complementary unsupervised approach, hierarchical clustering, to delineate distinct phenotypes among ASyS patients with ILD.
Maxime Billotte, Thomas Moulinet, Alain Meyer, Houda Camara, Loïs Bolko, Kévin Didier, Sandra Dury, Bernard Bonnotte, Hervé Devilliers, Philippe Bonniaud, Guillaume Beltramo, Julien Campagne, Nadine Magy‐Bertrand, Aurore Chaudier, Simon Valentin, Roland Jaussaud, Paul Decker   +16 more
wiley   +1 more source

Nodules cutanés négligés révélant un adénocarcinome pulmonaire

The Pan African Medical Journal, 2016
Nous rapportons le cas d'un patient de 45 ans, tabagique chronique à raison de 20 paquets année qui s'est présentait en consultation d'oncologie médicale pour des nodules sous cutanés multiples au niveau de l'abdomen associés à une lésion ulcérée de l ...
Iliass El Alami, Hassan Errihani
doaj   +1 more source

Christian Bohr. Discoverer of Homotropic and Heterotopic Allostery

Acta Physiologica, Volume 241, Issue S734, July 2025.
ABSTRACT This essay recounts and revisits the scientific contributions of Christian Bohr, highlighting his pivotal role in discovering allostery about 120 years ago. Bohr's meticulous experimentation led to identifying two distinct forms of allostery: homotropic (single‐ligand) and heterotropic (multi‐ligand), the latter widely recognized as the Bohr ...
Niels Bindslev
wiley   +1 more source

Sur la perméabilité du poumon de grenouille

, 1927
SUR LA PERMÉABILITÉ DU POUMON DE GRENOUILLE Sur la perméabilité du poumon de grenouille (11) (-
Buytendijk, Frederik Jakobus Johannes
core   +1 more source

Recherches immunologiques sur la péripneumonie. XII - Conception immuno-pathogénique de la maladie

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1969
Une thèse est présentée selon laquelle l'atteinte lésionnelle primitive de la péripneumonie bovine est lymphatique et est consécutive à la création d'un phénomène d'ARTHUS intraganglionnaire dans les ganglions lymphatiques drainant le poumon. L'hypothèse
Alain Provost
doaj   +1 more source

An antisense oligonucleotide targeting the heat‐shock protein HSPB5 as an innovative therapeutic approach in pulmonary fibrosis

British Journal of Pharmacology, Volume 182, Issue 12, Page 2713-2729, June 2025.
Background and Purpose Idiopathic pulmonary fibrosis (IPF) is a fatal disease characterized by fibroblast activation and abnormal accumulation of extracellular matrix in the lungs. We previously demonstrated the importance of the heat shock protein αB‐crystallin (HSPB5) in TGF‐β1 profibrotic signalling, which suggests that HSPB5 could be a new ...
Pierre‐Marie Boutanquoi, Lenny Pommerolle, Lucile Dondaine, Julie Tanguy, Pierre‐Simon Bellaye, Léo Biziorek, Marine Gautier‐Isola, Bernard Mari, Denis Masnikov, Palma Rocchi, Pascal Finetti, Patricia Korczak, Brune Vialet, Philippe Barthelemy, Carmen Garrido, Philippe Bonniaud, Olivier Burgy, Françoise Goirand   +17 more
wiley   +1 more source

Endo‐Epicardial vs. Endocardial‐Only Catheter Ablation of Ventricular Tachycardia in Patients With Ischemic Cardiomyopathy: The EPIC‐VT Trial Design

Journal of Cardiovascular Electrophysiology, Volume 36, Issue 5, Page 1038-1045, May 2025.
ABSTRACT Introduction Radiofrequency ablation is a cornerstone therapy for patients with ischemic cardiomyopathy (ICM) presenting with ventricular tachycardia (VT). In this context, ablation is typically performed endocardially as a first‐line approach.
Raphaël P. Martins, Pierre Groussin, Francis Bessière, Laure Champ‐Rigot, Jean‐Baptiste Gourraud, Sophie Lepage, Jacques Mansourati, Grégoire Massoulie, Philippe Maury, Sandro Ninni, Bertrand Pierre, Frédéric Sacher, Emilie Varlet, Xavier Waintraub, Clara Locher, Dominique Pavin, Philippe Mabo, Christophe Leclercq, Karim Benali   +18 more
wiley   +1 more source

Factors mediating the association between socioeconomic status and lung cancer risk

Revue des Sciences de la Santé
Le revenu, l’éducation et l’emploi sont souvent utilisés comme indicateurs du statut socio-économique(SSE), chacun renseignant probablement sur des dimensions différentes. Ce n’est cependant pas clair si l’association entre chaque indicateur du SSE et le
Thomas MATUKALA NKOSI, Marie-Elise PARENT, Jack SIEMIATYCKI, Belinda NICOLAU, Marie-Claude ROUSSEAU   +4 more
doaj   +1 more source

Pneumothorax spontané simultanément bilatéral

The Pan African Medical Journal, 2016
Le pneumothorax est un épanchement gazeux entre la plèvre viscérale et la plèvre pariétale. Le pneumothorax spontané est exceptionnellement bilatéral d'où la particularité de cette observation.
Hicham Souhi, Hanane El Ouazzani
doaj   +1 more source