Results 171 to 180 of about 816,124 (307)
Long-term poverty, rurality, and geographic disparities in colorectal cancer: a spatial analysis in Texas. [PDF]
Ramphul R +7 more
europepmc +1 more source
Poverty or Poverties? A Discussion about the Multiple Approaches of Poverty
Resumo: Desde que o tema da pobreza passou a ganhar ênfase, o que ocorreu por volta do século XVIII, o debate conceitual se limitava à questão de seu caráter absoluto ou relativo e das condições mínimas de sobrevivência. Já o destaque dado nos últimos anos à pobreza é acompanhado, nos mais diversos estudos, pela ampliação da sua concepção.
openaire +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Assessing the impact of social determinants of health on rising preterm birth trends in England. A longitudinal ecological study, 2012-17. [PDF]
Wilcock A +3 more
europepmc +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Mapping territorial labour-related well-being inequalities in Ecuador: A multivariate geometric approach. [PDF]
Serrano Orellana BJ.
europepmc +1 more source

