Results 101 to 110 of about 1,000,650 (308)
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Pobreza: ¿Una salida del túnel?
El artículo discute la manera de estudiar la pobreza, principalmente en los países atrasados y, en particular, en América Latina. Las formas de medición a las que conduce una conceptualización nueva sobre este fenómeno, plantea, también, nuevas formas ...
Pierre Salama
doaj
Relationship between Income-poverty and Food insecurity in Rural Far-western Mid-hills of Nepal [PDF]
For the purpose of this study, sample was selected through stratified random sampling from Baitadi district, which falls in rural Far-western Hills of Nepal.
Joshi, Niraj Prakash +1 more
core +1 more source
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Social Policy Trends: What Does The Poverty Line Measure?
The federal government identifies who is experiencing poverty by comparing household incomes to a measure called the Poverty Line. What does this poverty line measure? Lifting people out of poverty is an important public policy goal.
Ronald Kneebone, Margarita Wilkins
doaj +1 more source
Factors affecting the healthcare utilization from Shasthyo Suroksha Karmasuchi scheme among the below-poverty-line population in one subdistrict in Bangladesh: a cross sectional study. [PDF]
Hasan MZ +6 more
europepmc +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Modern approaches to studying the phenomenon of poverty
The article is devoted to the main modern approaches and interpretations of the concept of poverty. Various types of poverty and categories of poor people are considered, the main causes of poverty are shown.
D. A. Popravko
doaj
Quantifying the magnitude and severity of absolute poverty in the developing world in the mid-1980s [PDF]
In counting the poor, and measuring the severity of absolute poverty, one faces a number of difficult questions. What poverty line should be used? Should one use the same poverty line across all countries?
Chan, Elaine +3 more
core
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source

