Results 71 to 80 of about 1,000,650 (308)

Poverty and Casino Gambling in Buffalo [PDF]

open access: yes, 2011
The Buffalo Creek Casino will exacerbate Buffalo’s poverty. Casinos, especially urban casinos, attract many gamblers living at or near the poverty line, and problem or pathological gamblers often fall from the middle class into poverty.
Magavern, Sam, Mulé, Elaina
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Dollar a day revisited [PDF]

open access: yes
The paper presents the first major update of the international"$1 a day"poverty line, first proposed in 1990 for measuring absolute poverty by the standards of the world's poorest countries.
Chen, Shaohua   +2 more
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Real Quality of Life vs Extended Representations of Your Own Clear Exterior

open access: yesУправленческое консультирование, 2019
The relevance. The article is devoted to the consideration of a question that would seem to be of a purely medical and philosophical nature, when a person, under aggressive influence and sophisticated pressure of the media, chooses a pattern of his ...
A. N. Tsatsulin, B. A. Tsatsulin
doaj   +1 more source

The Poverty Burden: A Measure of the Difficulty of Ending Extreme Poverty [PDF]

open access: yes
In this paper, we consider an extension of the commonly used poverty gap measure that may be used to address he question of whether the elimination of poverty is a feasible objective, given sufficient political commitment.
John Quiggin, Renuka Mahadevan
core  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Statistically Significant Changes in the Poverty-Rate, 1997-98 to 2002-03 [PDF]

open access: yes
Sampling variation should be taken into account when sample data are used to estimate changes in the poverty rate over time. This paper reports poverty rates and their standard errors, calculated using data from the 1997-98 and 2002-03 Surveys of Income ...
Rodgers, J.R.
core  

The Measure of Poverty: A Boston Indicators Project Special Report [PDF]

open access: yes, 2011
Examines Boston's poverty rate by race/ethnicity, family structure, education, and geography; income inequality; demand for safety-net programs; and how the high cost of living and budget cuts affect vulnerable households and those below the poverty ...
Charlotte B. Kahn, Jessica K. Martin
core  

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