Results 71 to 80 of about 20,964 (255)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Spatial Distribution of Poverty in Chile
Estudios de Economía, 2016 Chile’s recent success in reducing poverty has been remarkable, with poverty rates falling by approximately two-thirds over the last 20 years. However, further gains against poverty may be inhibited by the increasing difficulty associated with ...
Claudio Agostini
doaj
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Mapping Fuel Poverty in Portugal
Energy Procedia, 2016 Abstract We defined a novel methodology to assess the potential fuel poverty of residential dwellings at LAU2 level combining data on income, level of education, unemployment rate, and number of inhabitants above 65 years old, with both the space heating and cooling gap estimated per household typology.
Simoes, Sofia G. +2 more
openaire +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Jurnal Ekonomi Pembangunan: Kajian Masalah Ekonomi dan Pembangunan, 2015 This research aims to compile the programs for poverty alleviation by community empowerment model and review the determination program as effectiveness evaluation poverty alleviation program which still can’t be worked properly.
Sutikno Sutikno +3 more
doaj
Assessing the spatial variation of water poverty determinants in Maharashtra, India
Water PolicyWater scarcity is an emerging multidimensional issue concerning not only the physical availability of resources but also is linked with poverty. The existing literature has established a relationship between income poverty and water poverty.
Aishwarya Dhawan, Haripriya Gundimeda
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source