Results 121 to 130 of about 6,200,732 (391)

Decentralisation and Poverty Reduction [PDF]

OECD Development Centre Policy Insights, 2005
Decentralisation has become a key issue in development policy in the past two decades. Whereas the advantages and risks of transferring power and resources to local tiers of government have been debated for quite some time, it is only very recently that the linkages between decentralization and poverty reduction have been addressed. This Policy Insight
openaire   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

The dynamics of poverty: Why don't "the poor" act collectively? [PDF]

Hunger, Types of poverty, Escaping poverty, Poverty reduction, Housing support, Reasons for descent into poverty,
Krishna, Anirudh
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Determinants of Poverty in Pakistan: A Multinomial Logit Approach

Lahore Journal of Economics
According to the World Development Report 2000-2001 almost half of the world’s population – 2.8 billion out of 6 billion live on less than $2 a day; while a fifth, i.e., 1.2 billion live on less than $1 a day with 44 per cent of them living in South ...
Umer Khalid, Lubna Shahnaz and Hajira Bibi
doaj  

Property rights for poverty reduction: [PDF]

Property rights, Poverty reduction, Hunger, Poverty dynamics, Food policy, food security, Pro-poor growth, Capacity building, Vulnerability, Gender, Multiple use, Devolution,
Kameri-Mbote, Patricia, Markelova, Helen, Meinzen-Dick, Ruth Suseela   +2 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Exploring honey-derived compounds as potential inhibitors of NDRG1 for breast cancer treatment under hypoxic conditions: a multiomics profiling, molecular docking, and molecular dynamics study

Future Journal of Pharmaceutical Sciences
Background Hypoxia has been recognized as a major contributor to cancer progression. Targeting hypoxia-derived factors, particularly in breast cancer, may present an auspicious strategy for cancer therapy. Honey-derived natural products have demonstrated
Wira Eka Putra, Arief Hidayatullah, Diana Widiastuti, Muhammad Fikri Heikal, Sustiprijatno Sustiprijatno   +4 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source