Results 221 to 230 of about 1,661,808 (287)

The c‐Src inhibitor eCF506 diminishes opioid tolerance and reduces β‐arrestin2 recruitment

open access: yesBritish Journal of Pharmacology, EarlyView.
Morphine activation of μ receptors causes tolerance through c‐Src activation and β‐arrestin2 recruitment. c‐Src inhibition or degradation reduces β‐arrestin2 recruitment, μ receptor endocytosis, while causing receptor upregulation, all likely contributing to reduced morphine tolerance.
Samuel Singleton   +6 more
wiley   +1 more source

Assessment of Different Technologies in the Fabrication of 3D Printed Tooth Models for Dental Education

open access: yesEuropean Journal of Dental Education, EarlyView.
ABSTRACT Background 3D printing has emerged as a practical method for fabricating customisable, accurate and affordable dental training models. Numerous 3D printing technologies exist, though there is no standardised comparison to inform their implementation in dental education.
Samuel Bereza   +5 more
wiley   +1 more source

Fatigue of AM TiAl6V4: Probabilistic Modelling of the Size Influence as a Transfer Method From Test Specimen to Part

open access: yesFatigue &Fracture of Engineering Materials &Structures, EarlyView.
ABSTRACT This paper investigates the fatigue behavior of additively manufactured TiAl6V4 by comparing two specimen geometries with different highly stressed volumes. A fracture mechanical approach based on the El‐Haddad–Smith–Topper model is combined with defect analysis through X‐ray computed tomography.
Sebastian Mansky   +2 more
wiley   +1 more source

Merkel cell carcinoma: an updated guide for pathologists

open access: yesHistopathology, EarlyView.
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine carcinoma for which the differential diagnosis can include other small cell malignancies (especially metastatic small cell carcinoma) or cutaneous carcinoma. Morphologic and immunophenotypic aberrancies in MCC can increase diagnostic challenge.
Paul W. Harms
wiley   +1 more source

The use of thermal imaging to assess heat generation during dental implant bed preparation in the presence of a surgical guide with an incorporated coolant channel

open access: yesJournal of Prosthodontics, EarlyView.
Abstract Purpose This study evaluates the thermodynamic benefits of including an irrigation fluid channel in the design of surgical guides used for dental implant site drilling. Materials and Methods Two types of guides suitable for hosting artificial bone plates that mimic the mechanical properties of human alveolar bone were designed: a classical ...
Robert‐Angelo Tuce   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy