Results 71 to 80 of about 396,237 (268)

Autographic measurements of the quenching power of liquids [PDF]

open access: yesJournal of the Franklin Institute, 1919
n ...
openaire   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

The Design and Validation of an Intensity-Modulated Multipoint Fiber-Optic Liquid-Level Sensor

open access: yesSensors
This study introduces a cost-effective solution and sensor arrays for the multipoint liquid-level measuring sensor based on an intensity modulation technique.
Abdul Ghaffar   +9 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Research and application of remote intelligent fluid supply and power supply technology in coal mine super-long strike fully mechanized caving face

open access: yesMeitan kexue jishu
In the working conditions of long-strike coal mine faces, the traditional approach for liquid supply and power supply equipment is mobile withdrawal to follow the mining progress. However, this production method has several drawbacks. It involves a large
Chuanming ZHANG   +5 more
doaj   +1 more source

A liquid progressive multifocal lens adjusted by the deformation of a non-uniform elastic membrane due to the variation of liquid pressure

open access: yesJournal of the European Optical Society-Rapid Publications, 2018
Background In this paper, a liquid progressive multifocal lens with solid-liquid structure is demonstrated, which mainly consists of two elastic polydimethylsiloxane (PDMS) membranes, a solid substrate and liquid. Methods To realize the adjustment of the
Weiliang Jia, Dong Xiang, Songjing Li
doaj   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand   +5 more
wiley   +1 more source

Visualization of Liquid Lifting Process of Multiple Tube Bubble Pump

open access: yesZhileng xuebao, 2020
The gas–liquid two-phase flow characteristics in the riser of the bubble pump directly affects its working substance lifting performance. A high-speed camera system was set-up to visualize the lifting process of multiple tube bubble pump under different ...
Zhang Ke   +3 more
doaj  

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