Results 111 to 120 of about 16,330,143 (357)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

An Integrated Strategy to Treat and Control Acid Mine Drainage from Waste Rock and Underground Workings at the Former Franklin Mine in Nova Scotia, Canada: Field Performance Monitoring

open access: yesPollutants
Acid mine drainage (AMD), which is primarily caused by the exposure of sulfidic minerals to oxygen and water during mining operations, remains a significant contributor to environmental pollution.
Christopher Power
doaj   +1 more source

Travels with a Donkey: further adventures in social research [PDF]

open access: yes, 2009
Alvesson M.   +17 more
core   +1 more source

The 24 hour challenge: creating a multidiscipline environment for design and entrepreneurship in engineering and design. Enhancing Employability through Enterprise Education [PDF]

open access: yes, 2014
This Innovation and Creative Exchange (ICE) is an inter-school enterprise opportunity exclusively for second year Engineering and Design students at the University of Huddersfield.
Power, Jess
core  

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Luckily He Backed Off

open access: yesColumbia Social Work Review, 2019
Women’s sexual beliefs and behaviors are influenced by the overarching demands of society. This paper discusses a portion of a study completed at a small liberal arts institution in the northeastern United States.
Kelsey Power
doaj  

Mobilising the East: Some Notes on Robert Guédiguian's Le voyage en Arménie

open access: yesAnnali Online dell'Università di Ferrara. Sezione Lettere, 2013
Nella società francese, a partire dallo sgretolamento del suo ruolo di potenza coloniale verso la fine degli anni Cinquanta del secolo scorso, si sono verificati significativi cambiamenti di paradigma.
Aidan Power
doaj   +1 more source

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