Results 71 to 80 of about 4,965,450 (253)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

High Efficiency Power Amplifier Based on Envelope Elimination and Restoration Technique [PDF]

, 2010
Due to complex envelope and phase modulation employed in modern transmitters it is necessary to use power amplifiers that have high linearity. Linear power amplifiers (classes A, B and AB) are commonly used, but they suffer from low efficiency especially
Alou Cervera, Pedro, Cobos Márquez, José Antonio, Gimeno Martín, Alejandro, Vasic, Miroslav, Pardo Martin, José Manuel, Ortega González, Francisco Javier, Oliver Ramírez, Jesús Angel, Díaz López, Daniel, Benavente Peces, César, García Suárez, Oscar   +9 more
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Coupled experiment/simulation approach for the design of radiation-hardened rare-earth doped optical fibers and amplifiers [PDF]

, 2011
We developed an approach to design radiation-hardened rare earth -doped fibers and amplifiers. This methodology combines testing experiments on these devices with particle swarm optimization (PSO) calculations.
F. Prudenzano, Mescia, L, Vivona, M., Girard, S, Boukenter, Aziz, A. Boukenter, Goiffon, V, Cannas, M., V. Goiffon, Mescia, Luciano, Boukenter, A, L. Mescia, Vivona, Marilena, Mescia, L., R. Boscaino, Cadier, B., P. Paillet, Paillet, P., Y. Ouerdane, Boukenter, A., Paillet, P, Paillet, Philippe, Marcandella, C, Cadier, Benoît, S. Girard, A. Laurent, Laurent, A, Robin, T, C. Marcandella, Goiffon, Vincent, Cadier, B, Ouerdane, Y., Ouerdane, Y, Girard, Sylvain, Prudenzano F, Robin, Thierry, F. Robin, Prudenzano, F, Laurent, Arnaud, Boscaino, Roberto, T. Robin, Robin, T., B. Cadier, Marcandella, C., Goiffon, V., Cannas, Marco, M. Cannas, Prudenzano, F., Boscaino, R., Prudenzano, Francesco, Ouerdane, Youcef, M. Vivona, Girard, Sébastien, Marcandella, Claude, Laurent, A.   +54 more
core   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Signal amplifiers in optical communication systems

Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska
This work focuses on modelling an optical soliton-based pulse amplitude modulation (PAM) system incorporating linear semiconductor optical amplifiers (LSAs).
Nurzhigit Smailov, Nurlybek Turar, Akezhan Sabibolda   +2 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Energy-Efficient Aggressive Duty-Cycling of V-Band Power Amplifiers

IEEE Access
In addition to implementing the core functionality, a design goal for modern circuits is reduced energy consumption. When options for improving active state efficiency are eventually exhausted, the next step is to aggressively minimize the duration a ...
Maximilian Gottfried Becker, Marco Gunia, Diego Mendez, Frank Ellinger   +3 more
doaj   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source