Results 81 to 90 of about 6,551,596 (304)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

A characteristic oriented probabilistic stability assessment method based on physics-informed neural network for stochastic power system

open access: yesInternational Journal of Electrical Power & Energy Systems
The significant stochasticity introduced by renewable energy and flexible loads challenges traditional deterministic stability methods in power system. To address the stability challenges posed by stochastic disturbances, by integrating physics-informed ...
Jingxian Li   +5 more
doaj   +1 more source

The Characteristic Features of Japan’s Soft Power in Central Asia

open access: yesЕжегодник Япония, 2022
The article analyses the role of soft power in the process of shaping and carrying out of Japan’s foreign policy towards Central Asia. Using cultural affinity as a basis Japan seeks to build an attractive image in the region.
O. Dobrinskaya
doaj  

Thermal characteristic research of associated power devices based on three-level inverters and power-loss calculation

open access: yesCase Studies in Thermal Engineering, 2018
To reduce the size and improve the power density of three-level inverters, two or more associated power devices are assembled on the same heatsink, which, however, has a great influence on the thermal characteristics of heatsink because of heat ...
Shi-Zhou Xu   +4 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Quadratic Euler characteristic of symmetric powers of curves

open access: yesmanuscripta mathematica
Abstract We compute the quadratic Euler characteristic of the symmetric powers of a smooth, projective curve over any field k that is not of characteristic two, using the Motivic Gauss–Bonnet Theorem of Levine–Raksit. As an application, we show that the power structure on the Grothendieck–Witt ring introduced by Pajwani–Pál computes the ...
Bröring, Lukas F., Viergever, Anna M.
openaire   +4 more sources

Siting new energy infrastructure in Ohio a guidance document.

open access: yes, 2005
Title from cover of PDF document (viewed Apr. 19, 2006).; "February 2005."; Harvested from the web on 4/20/06Introduction -- Power siting in Ohio: Ohio Power Siting Board ; Siting process in Ohio -- Incentives: Ohio Air Quality Development Authority ...
Ohio Power Siting Board.
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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