Results 231 to 240 of about 1,138,201 (295)

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Exploring the regulatory potential of RNA structures in 202 cyanobacterial genomes. [PDF]

Nucleic Acids Res
Geissler AS, Carrasquer-Alvarez E, Anthon C, Frigaard NU, Gorodkin J, Seemann SE.   +5 more
europepmc   +1 more source

Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP‐Mediated Invasion Activates Ras Signaling and Destabilizes p53

Advanced Science, EarlyView.
ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang, Jia Zhang, Haojie Lu, Jingjing Ni, Shuaishuai Yang, Yuting Shi, Shuo Zhang, Pei Zhang, Li Liu   +8 more
wiley   +1 more source

Laser power stabilization using conservation law in acoustic optic modulator. [PDF]

Sci Rep
Li E, Ma Q, Wang W, Du B, Liu G.
europepmc   +1 more source

Spatiotemporal evolution and driving mechanisms of multiple scales ecological security in Shanxi Province from the perspective of service, risk and health. [PDF]

Sci Rep
Dang G, Li G, Hu J.
europepmc   +1 more source

Understandings and critiques of biocultural diversity conservation and future recommendations for conservation actors. [PDF]

Conserv Biol
York NDL.
europepmc   +1 more source

Integrated tunable green light source on silicon nitride. [PDF]

Light Sci Appl
Wang G, Yakar O, Ji X, Clementi M, Zhou J, Lafforgue C, Wu J, Hu J, Kippenberg TJ, Brès CS.   +9 more
europepmc   +1 more source

Rehabilitation and release of White-tailed Eagles (<i>Haliaeetus albicilla</i>) in Bulgaria: A case study. [PDF]

Biodivers Data J
Petrov R, Marutsova V, Popov D, Arkumarev V, Stamenov A, Gradev G, Klisurov I.   +6 more
europepmc   +1 more source