Results 41 to 50 of about 446,106 (266)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Abnormal behaviour analysis algorithm for electricity consumption based on density clustering
The Journal of Engineering, 2019 How to effectively detect abnormal electricity consumption behaviour from a large-scale electrical load data is very important to smart grid. An abnormal electricity consumption analysis method based on density clustering is proposed.
Min Xiang +4 more
doaj +1 more source
Balancing power consumption in multiprocessor systems
ACM SIGOPS Operating Systems Review, 2006 Actions usually taken to prevent processors from overheating, such as decreasing the frequency or stopping the execution flow, also degrade performance. Multiprocessor systems, however, offer the possibility of moving the task that caused a CPU to overheat away to some other, cooler CPU, so throttling becomes only a last resort taken if all of a system'
Merkel, Andreas, Bellosa, Frank
openaire +4 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
SITRUS: Semantic Infrastructure for Wireless Sensor Networks
Sensors, 2015 Wireless sensor networks (WSNs) are made up of nodes with limited resources, such as processing, bandwidth, memory and, most importantly, energy. For this reason, it is essential that WSNs always work to reduce the power consumption as much as possible ...
Kalil A. Bispo +2 more
doaj +1 more source
Simulation of SSD’s Power Consumption
, 2017 In order to avoid changing existing infrastructures, SSDs need to fit in the same physical space of HDDs and, therefore, in their power envelope. Unfortunately, NAND power consumption is strongly dependent upon the Flash operation (i.e. read, write, erase).
Zuolo, Lorenzo +4 more
openaire +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
IoTNarrowband Internet of Things (NB-IoT) is widely used for connecting low-power devices that must operate for years without maintenance. To design reliable systems, it is essential to understand how much energy these devices consume under different ...
Valters Skrastins +4 more
doaj +1 more source
Sensors, 2017 Fog computing extends cloud computing to the edge of a network enabling new Internet of Things (IoT) applications and services, which may involve critical data that require privacy and security.
Manuel Suárez-Albela +3 more
doaj +1 more source