Results 71 to 80 of about 6,772,662 (289)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Sensors, 2017 Fog computing extends cloud computing to the edge of a network enabling new Internet of Things (IoT) applications and services, which may involve critical data that require privacy and security.
Manuel Suárez-Albela +3 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Classifying Proprietary Firmware on a Solid State Drive Using Idle State Current Draw Measurements
IEEE Access, 2020 Solid state drives (SSDs) are coming under increased scrutiny as their popularity continues to grow. SSDs differ from their hard disk drive predecessors because they include an onboard layer of firmware to perform required maintenance tasks related to ...
T. Owens Walker +8 more
doaj +1 more source
Balancing power consumption in multiprocessor systems
ACM SIGOPS Operating Systems Review, 2006 Actions usually taken to prevent processors from overheating, such as decreasing the frequency or stopping the execution flow, also degrade performance. Multiprocessor systems, however, offer the possibility of moving the task that caused a CPU to overheat away to some other, cooler CPU, so throttling becomes only a last resort taken if all of a system'
Merkel, Andreas, Bellosa, Frank
openaire +4 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Electric Power Consumption Forecasting in Bulgaria
Engineering ProceedingsThe primary goal of this paper is to develop a robust model for forecasting electric power consumption in Bulgaria. Leveraging historical forecast data from Open-Meteo for weather-related features and ENTSOE data, our objective is to create an accurate ...
Petko Ivanov Stoev +3 more
doaj +1 more source
Efficient Parallel-Beamforming Based on Shared FIFO for Ultra-Compact Ultrasound Imaging Systems
IEEE Access, 2020 The realization of a parallel-beamforming (pBF) method in ultra-compact ultrasound imaging systems is challenging to achieve uncompromised beamforming accuracy in limited hardware and power resources.
Jeeun Kang +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source