Results 61 to 70 of about 5,844,916 (295)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Impact of wind power on the unit commitment, operating reserves and market design [PDF]

, 2011
Paper presented at the 2011 IEEE Power and Energy Society General Meeting, San Diego, CA, 24-29 July 2011This article highlights and demonstrates the new requirements variable and partly unpredictable wind power will bring to unit commitment and power ...
Milligan, M., Lange, B., Gibescu, M., Michael Milligan, Hannele Holttinen, Lange, Bernard, Kiviluoma, K., Juha Kiviluoma, Meibom, P., Meibom, Peter, O\u27Malley, Mark, Peter Meibom, Madeleine Gibescu, Kiviluoma, Juha; id_orcid, Tuohy, Aidan, Holttinen, H., Tuohy, A., Gibescu, Madeleine, Holttinen, Hannele, O'Malley, M., Milligan, Michael R., Bernhard Lange, Kiviluoma, Juha, Aidan Tuohy, O'Malley, Mark, Mark O'Malley, Kiviluoma, J.   +26 more
core   +1 more source

One-Shot Fault Diagnosis of Wind Turbines Based on Meta-Analogical Momentum Contrast Learning

Energies, 2022
The rapid development of artificial intelligence offers more opportunities for intelligent mechanical diagnosis. Fault diagnosis of wind turbines is beneficial to improve the reliability of wind turbines.
Xiaobo Liu, Hantao Guo, Yibing Liu
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Can conversion of CO2 into fuels via electrochemical or thermochemical reduction be energy efficient and reduce emissions?

, 2022
Electrochemical and thermochemical conversion of CO2 into fuels are significant carbon conversion technologies to mitigate carbon emissions. Based on the captured CO2, many previous studies carried out tech-economic and environmental analyses for the CO ...
Yang, Dongtai, Li, Sheng, Zheng, Yawen, He, Song   +3 more
core   +1 more source

Enhanced Grid-Connected Phase-Locked Loop Based on a Moving Average Filter

IEEE Access, 2020
Moving average filter (MAF)-based phase-locked loops (PLLs) have received considerable attention in recent years due to their attractive features. Indeed, they are able to completely eliminate the unwanted effect of harmonics, dc offset, and unbalanced ...
Cong Liu, Jiayan Jiang, Jianguo Jiang, Zhongzheng Zhou   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Pulsed power applications research: from super critical switches to renewable fuels

, 2014
Important aspects of pulsed power processing that up to now received little attention are opened and summarized. A start is made in dealing with these aspects.
E. J. M. van Heesch, J. Zhang, F. J. C. M. Beckers, Huiskamp, T., W. F. L. M. Hoeben, Hoeben, W.F.L.M.; id_orcid, T. Huiskamp, A. J. M. Pemen, van Heesch, E.J.M., Hoeben, W.F.L.M., Beckers, F.J.C.M., Pemen, A.J.M., Zhang, J.   +12 more
core   +1 more source

An Electromagnetic Load Identification Method Based on the Polynomial Structure Selection Technique

Shock and Vibration
Electromagnetic loads can effectively monitor motor health and improve motor design. Considering the weak correlation of the modal shape and Chebyshev orthogonal polynomial in the space-time independent electromagnetic load identification method, a ...
Wengui Mao, Shixiong Pei, Jie Guo, Jianhua Li, Buyao Wang   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source