Results 91 to 100 of about 4,720,670 (304)

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

A novel and easy‐to‐implement modulation scheme for reducing modulation complexity in modular multilevel converter

IET Power Electronics
Modulation strategy plays a key role in the operation of modular multilevel converters (MMC). Although many studies have been carried out on its optimization in MMC, the limitations of hardware implementation are seldom considered.
Zichen Wang, Zhijie Liu, Ke‐Jun Li, Jinxin Dou, Zhonglin Guo, Xiaoxue Ge   +5 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

BPA Prepares for the 21st Century.

, 1998
This is a brief review of the state of the Bonneville Power Administration. It reviews BPA`s competitive status, fish and wildlife funding, cost structure of the federal system, subscription sales of electricity, emergency cost recovery, cost reduction ...
United States. Bonneville Power Administration.
core   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Test Results From a Pair of 1-kWe Dual-Opposed Free-Piston Stirling Power Convertors Integrated With a Pumped NaK Loop [PDF]

, 2011
As a step towards development of Stirling power conversion for potential use in Fission Surface Power (FSP) systems, a pair of commercially available 1-kW-class free-piston Stirling convertors were modified to operate with a NaK (sodium (Na) and ...
Geng, Steven M., Godfroy, Thomas J., Pearson, J. Boise, Briggs, Maxwell H., Penswick, L. Barry   +4 more
core  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Ripple‐Free Input Current Quadratic Converter Based on Watkin–Johnson Topology

IET Power Electronics
This article proposes a power electronics converter capable of providing high voltage gain while keeping a high‐quality input current ripple operating with low duty cycle. The technique for achieving the zero input current ripple at a selected duty cycle
Brenda Lizeth Reyes‐García, Pedro Martín García‐Vite, Hector R. Robles‐Campos, Marco Antonio Coronel‐García, Julio C. Rosas‐Caro, Francisca Hernández Angel   +5 more
doaj   +1 more source

Personality profile and its association with conversion to neurodegenerative disorders in idiopathic REM sleep behavior disorder. [PDF]

NPJ Parkinsons Dis, 2022
Zhou L, Chau SWH, Liu Y, Wang J, Zhang J, Chan NY, Chan JWY, Huang B, Chen S, Li SX, Mok VCT, Wing YK.   +11 more
europepmc   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source