Results 81 to 90 of about 2,226,241 (294)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Predictive control of wind turbines by considering wind speed forecasting techniques [PDF]

open access: yes, 2009
A wind turbine system is operated such that the points of wind rotor curve and electrical generator curve coincide. In order to obtain maximum power output of a wind turbine generator system, it is necessary to drive the wind turbine at an optimal rotor ...
Jovanovic, Milutin   +3 more
core  

Automated methodology for adjustment of component values in passive converter circuit for wind turbine generators [PDF]

open access: yes, 2012
The current paper proposes an automated design approach for a previously developed passive converter circuits for wind turbine generators. This suggested approach allows to calculate the components for all passive converter circuits approved in European ...
Bekov, Emilian   +3 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

A Comprehensive Cleaning Method for Outliers in Wind Turbine Power Curves Based on the Quartile Method and Segmented Regression Detection Method

open access: yesEnergies
The actual power curve of a wind turbine is essential for performance evaluation and operational optimization. However, SCADA data frequently contain various abnormal data points that limit their direct and effective use.
Xiaolong Shang   +7 more
doaj   +1 more source

Offshore Wind Energy Resource Atlas of Asturias (N Spain)

open access: yesProceedings, 2018
This work assesses for the first time the offshore wind energy resource in Asturias, a region in the North of Spain. Numerical model and observational databases are used to characterize the gross wind energy resource at different points throughout the ...
Mario López   +2 more
doaj   +1 more source

Scaling behavior in the $\beta$-relaxation regime of a supercooled Lennard-Jones mixture

open access: yes, 1994
We report the results of a molecular dynamics simulation of a supercooled binary Lennard-Jones mixture. By plotting the self intermediate scattering functions vs. rescaled time, we find a master curve in the $\beta$-relaxation regime.
B. Kim   +15 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Semistability of Certain Bundles on Second Symmetric Power of a Curve

open access: yes, 2015
Let $C$ be a smooth irreducible projective curve and $E$ be a rank 2 stable vector bundle on $C$. Then one can associate a rank 4 vector bundle $\mathcal{F}_2(E)$ on $S^2(C)$, second symmetric power of $C$.
Dan, Krishanu, Pal, Sarbeswar
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

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