Results 151 to 160 of about 7,767,553 (313)

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Increasing the power density of electrohydrodynamic pumps by mapping the fluid landscape. [PDF]

Sci Adv
Luo Y, Schouten M, Shea H.
europepmc   +1 more source

India sketchbook [picture] /

, 1930
Title devised by cataloguer.; Part of the John Power sketchbooks collection.; Inscriptions: "India"--In pencil on front cover.; Condition: Yellowing, soiled, stained.; Also available online at: http://nla.gov.au/nla.pic-vn6293781; Exhibited: Abstraction ...
Power, J. J. W. (John Joseph Wardell), 1881-1943.
core  

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Proton-shuttling nanosheet membranes enable high-power-density protonic fuel cells. [PDF]

Sci Adv
He K, Wang Y, Dong D, Wang F, Ung K, Wang Z, Li Z, Zhang X, Tao S, Jasieniak JJ, Webley PA, MacFarlane DR, Liu JZ, Shao Z, Wang H.   +14 more
europepmc   +1 more source

Ireland sketchbook [picture] /

, 1930
Title devised by cataloguer.; Part of the John Power sketchbooks collection.; Inscriptions: "Ireland"--In pencil on front cover.; Condition: Yellowing, soiled, stained, tears, loss.; Also available online at: http://nla.gov.au/nla.pic-vn6293748 ...
Power, J. J. W. (John Joseph Wardell), 1881-1943.
core  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Synergistic dual anion regulation unlocks giant thermopower and power density in hydrogel. [PDF]

Nat Commun
Li H, Gu Z, Zhu Y, Jiao Z, Tian J, Li Y, Chai Y, Chi X.   +7 more
europepmc   +1 more source