Results 41 to 50 of about 13,123,197 (246)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Dynamic equivalencing of distribution network with embedded generation [PDF]

, 2012
Renewable energy generation will play an important role in solving the climate change problem. With renewable electricity generation increasing, there will be some significant changes in electric power systems, notably through smaller generators ...
Feng, Xiaodan Selina
core   +3 more sources

Facilitating power system transformation at the distribution network level

, 2023
The ongoing transformation of the electricity sector involves the connection of increasing amounts of controllable generation, storage, and consumption devices at the distribution network level.
Hesamzadeh, Mohammad Reza,, Biggar, Darryl,   +1 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Power Supply Capability Evaluation of Urban Distribution Network

, 2018
Urban distribution network is an important link for users, and it is of great social and economic significance to carry out scientific evaluation on power supply capacity of urban distribution network.
Dianping ZHAO, Bai XIAO, Zhuo JIANG, Yonggang SHI, Mingxi JIAO   +4 more
core   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Lightweight, High-Efficiency, High-Dynamic-Response and Low-Ripple DC-DC Converters Based on Interleaved Magnetic Integrated Switched-Coupled Inductor for Electric Propulsion Aircraft

Aerospace
With the development of distributed electric propulsion aircraft, researching airborne high-efficiency, high-power-density, high-gain, high-dynamic and low-ripple, low-stress DC-DC that meets aviation standards is an urgent and profoundly challenging ...
Rui Guo, Hongkai Gao, Li Chen, Yiyi Zhang, Lei Wang   +4 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

A load forecasting method for IESs using TimeVAE and transfer learning

Zhejiang dianli
In this paper， an integrated learning approach based on time variational autoencoder （TimeVAE） and transfer learning （TL） is proposed to address the accuracy degradation in integrated energy systems （IESs） load forecasting caused by insufficient ...
CHEN Zhe, ZHOU Jinhui, JIN Donghui, CHEN Jiguang, MA Hengrui, ZHANG Jiaxin, ZHU Suxun   +6 more
doaj   +1 more source