Results 41 to 50 of about 1,527,487 (300)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Collaborative configuration of renewable energy and energy storage under fixed investment in the decarbonization process

Frontiers in Energy Research
In the process of decarbonization, the configuration of renewable energy and energy storage plays a crucial role. In current research, there is often a singular focus on the isolated optimization of either renewable energy configurations or energy ...
Jinlin Liao, Jinlin Liao, Guilian Wu, Guilian Wu, Guilian Wu, Jinghao Li   +5 more
doaj   +1 more source

Probabilistic Power Distribution Planning Using Multi-Objective Harmony Search Algorithm [PDF]

Journal of Operation and Automation in Power Engineering, 2018
In this paper, power distribution planning (PDP) considering distributed generators (DGs) is investigated as a dynamic multi-objective optimization problem.
A. Rastgou, J. Moshtagh, S. Bahramara
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Research Status and Prospects of Distribution Network Planning Technology Based on Artificial Intelligence [PDF]

Dianli jianshe
[Objective] With large-scale access to distributed power sources， new energy storage， charging facilities， etc.， the physical， digital， and commercial forms of distribution networks have undergone profound changes.
LI Jingru, LI Hongjun, MA Liang, JIANG Shigong, MU Chaoxu, SI Chenyi
doaj   +1 more source

Massive Scenario Reduction Based Distribution-Level Power System Planning Considering the Coordination of Source, Network, Load and Storage

Zhongguo dianli, 2022
The integration of high-proportion renewable power generation has brought great challenges to the efficiency of distribution network planning methods and the economy of planning results.
Jinsen LIU, Ning LUO, Jie WANG, Chang XU, Yi Cao, Zhiwen Liu   +5 more
doaj   +1 more source

The Impact of Distributed Energy Resources on the Bulk Power System: A Deeper Dive [PDF]

, 2017
solar photovoltaics (PV), electric storage and electric \ vehicles, demand response, combined heat and \ power, wind, fuel cells, and micro-turbines are \ typically installed on the low or medium voltage \ distribution network.
Birk, Michael, Tabors, Richard
core   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Model selection and mechanism design for electricity markets in hydropower‐rich regions: Adaptation study

IET Generation, Transmission & Distribution, 2023
The development of foreign electricity markets has been relatively complete, while China's electricity market started late and the design of the market mechanism needs to be improved, so the selection of a suitable market model and the design of the ...
Fang Liu, Jianhang Liu, Xiu Yang
doaj   +1 more source

Adjustment of model parameters to estimate distribution transformers remaining lifespan [PDF]

, 2018
Currently, the electrical system in Argentina is working at its maximum capacity, decreasing the margin between the installed power and demanded consumption, and drastically reducing the service life of transformer substations due to overload (since the ...
Gotay Sardiñas, Jorge, Jimenez, Victor Adrian, Rodriguez, Sebastian Alberto, Will, Adrian L. E.   +3 more
core   +1 more source