Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Capacity-constrained renewable power generation development in light of storage cost uncertainty. ESRI Working Paper No. 647 December 2019 [PDF]
, 2019 The development of sustainable energy sources and their enabling infrastructures are often met by public opposition, resulting in lengthy planning processes.
Bertsch, Valentin +2 more
core
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Generalized linear‐constrained optimal power flow for distribution networks
IET Generation, Transmission & Distribution, 2023 Optimal power flow (OPF) plays an important role in the secure and economical operation of the distribution network. This paper proposes a novel generalized linear‐constrained optimal power flow (GLOPF) model for both radial and mesh distribution ...
Biao Li +4 more
doaj +1 more source
Power Distribution System Planning with Demand Uncertainty Consideration
Journal of Electrical Engineering and Technology, 2008 This paper proposes a method for solving distribution system planning problems taking into account demand uncertainty and geographical information. The proposed method can automatically select appropriate location and size of a substation, routing of feeders, and appropriate sizes of conductors while satisfying constraints, e.g.
Sirichai Wattanasophon +1 more
openaire +2 more sources
Reliability analysis of distribution network [PDF]
, 2014 The knowledge of the reliability of distribution networks and systems is important consideration in the system planning and operations for development and improvements of power distribution systems. To achieve the target as minimum interruptions as
Anthony, Roystone
core
Pylons in the back yard: local planning and perceived risks to health [PDF]
, 2007 Health fears arising from the presence of high-voltage power lines in residential areas have received recent attention in spatial planning. A study of stances taken by planning authorities in England and Wales shows their willingness to give expression ...
Aylesbury Vale District Council +33 more
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Contributions to Power Grid System Analysis Based on Clustering Techniques
Sensors, 2023 The topic addressed in this article is part of the current concerns of modernizing power systems by promoting and implementing the concept of smart grid(s).
Gheorghe Grigoraș +6 more
doaj +1 more source
Modeling and optimization of production and distribution of drinking water at VMW [PDF]
, 2011 We develop and discuss an operational planning model aiming at minimizing production and distribution costs in large drinking water networks containing buffers with free inflow.
B. Ulanicki +5 more
core +1 more source